DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and CLIPB2

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_312956.3	Gene:	CLIPB2 / 1273920	VectorBaseID:	AGAP003246	Length:	355	Species:	Anopheles gambiae

Alignment Length:	385	Identity:	123/385 - (31%)
Similarity:	182/385 - (47%)	Gaps:	75/385 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ILLLIASVSVVTEY---CDN---GTGECKELTPSDCP---VIFYNQHLIGAEVKY-----CDEF- 58
            ::|.:..|||..|.   |.|   .||:|  :...:|.   .|:..:.....|.::     |.|.
Mosquito     9 LVLALFGVSVALEQGQRCVNPARQTGKC--VLVRECASLLAIYSKRFTTPEETQFLASSRCGEIG 71

  Fly    59 -NDIVCCPIPLDHQNLKPAEQTR----PFEKQCKQYNEVRSACQSTPFIVGGTKASGKEFPFMAL 118
             ..:|||         ...:|||    |...:|        ..|.|..|:||.....:|||:.||
Mosquito    72 RKTLVCC---------ASEQQTRTSSFPTSPEC--------GIQVTDRIIGGQTTELEEFPWTAL 119

  Fly   119 IGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGELDYNST 183
            |...:|.   :..::.|||::::.:::||||||::: ..:..:|:.        |||||.|.::.
Mosquito   120 IEYRKPG---NQYDFHCGGALINARYILTAAHCVQS-LPRGWQLNG--------VRLGEWDLSTA 172

  Fly   184 TD--DALVQ----DFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCLP---PD 239
            .|  |.:..    |..:.::|.|.|||..|  ....|||||:.|.:....::.:..:|||   |.
Mosquito   173 NDCSDGICSAGPIDLEIESFVAHAGYDAAD--TAHTNDIALIRLRQDVASSEMIRPICLPLTEPQ 235

  Fly   240 -SGNDVQQVT-AAGWGFTADGVKSSHLLKVNLQRFSDEVCQKRLR-FSIDTR-TQFCAGSMSSQA 300
             |.|.|..|: |||||.|.....|...|||.|.......|::..| .:|..: :|.|||.:..:
Mosquito   236 RSRNRVGTVSFAAGWGKTESASASERKLKVELTVQDPSRCRQIYRGINIALKASQMCAGGLQGK- 299

  Fly   301 DTCNGDSGGPIFVQH--PLYPCLKQVIGIVSYGL-VCGSQGLPSVYTKVHLYTDWIESIV 357
            |||.||||||:..:.  ..|     :||:||:|| .||:.|.|.|||.|..|.|||||.|
Mosquito   300 DTCTGDSGGPLMAKSAGAWY-----LIGVVSFGLSKCGTAGYPGVYTNVVEYLDWIESNV 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	96/269 (36%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	93/266 (35%)
CLIPB2	XP_312956.3	CLIP	26..78	CDD:288855	11/53 (21%)
		Tryp_SPc	102..350	CDD:214473	93/267 (35%)
		Tryp_SPc	103..353	CDD:238113	96/269 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG25778
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920