DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and AgaP_AGAP003748

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_310280.7	Gene:	AgaP_AGAP003748 / 1271480	VectorBaseID:	AGAP003748	Length:	547	Species:	Anopheles gambiae

Alignment Length:	283	Identity:	105/283 - (37%)
Similarity:	145/283 - (51%)	Gaps:	54/283 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 FIVGGTKASGKEFPFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPN 165
            ||.||.:|..||||.||.||......|...:.:.||||::..|:|||||||...||
Mosquito    53 FIFGGRRAFLKEFPHMAAIGWTDKTVSPPVVQYKCGGSLIAAKYVLTAAHCKVDDE--------- 108

  Fly   166 FDSPKFV---------VRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKN----DIA 217
                |:|         ||||:.:..:|.||...|.|::|::.||        |:..||    |||
Mosquito   109 ----KYVFIRVIPPDTVRLGDTNLATTEDDETAQQFKIVSFAVH--------EKFKKNRKYYDIA 161

  Fly   218 LVELDRKAEFNDHVAAVCL-PPDSGNDV-QQVTAAGWGFT--ADGVKSSHLLKVNLQRFSDEVCQ 278
            |:||||:|:||..|..:|| |.|:.::. ..:.|.|:|||  ..|: |..|.||:|..:..:.|.
Mosquito   162 LIELDREAKFNTAVCPICLWPLDNIHEYSSSLRAIGFGFTTYTSGM-SPTLQKVSLNYYDSDSCN 225

  Fly   279 K------RLRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQ-HPLYPCLKQVIGIVSYGLVC-- 334
            .      |||:.: |..|||  :.:...|.|.||||||:.:. ..:...:..:.|:||:|..|
Mosquito   226 NELPKDARLRYGL-TSDQFC--TKTPHKDACLGDSGGPLQIDLSDVTRTIPYLTGVVSFGTGCWD 287

  Fly   335 GSQGLPSVYTKVHLYTDWIESIV 357
            ||.|   |||||..|.:||...|
Mosquito   288 GSMG---VYTKVASYINWIRERV 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	103/279 (37%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	101/276 (37%)
AgaP_AGAP003748	XP_310280.7	Tryp_SPc	54..305	CDD:238113	103/278 (37%)
		Tryp_SPc	54..303	CDD:214473	101/276 (37%)
		Trypsin	316..521	CDD:278516
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105391at6960
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920