DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and AgaP_AGAP007043

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_001237132.2	Gene:	AgaP_AGAP007043 / 1270058	VectorBaseID:	AGAP007043	Length:	575	Species:	Anopheles gambiae

Alignment Length:	304	Identity:	82/304 - (26%)
Similarity:	132/304 - (43%)	Gaps:	62/304 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 RPFEKQCKQYNEVRSAC---QSTP--FIVGGTKASGKEFPFMALIGTHRPNKSKSDINWDCGGSV 139
            :|||       ...|.|   :.:|  .:..|..|...::|:...:..|..::..:   :.||||:
Mosquito    27 QPFE-------VAASTCGVRRLSPMGLVTKGIIAEPGDWPWHVALFAHMKSEKPA---YKCGGSI 81

  Fly   140 VHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYD 204
            :...|||:||||::         :||.|  .:.::.|....|:..|.::|. :.:...::||.||
Mosquito    82 ISQHFVLSAAHCIK---------EPNPD--HYFLKAGIHHLNNDNDTSVVV-YNLFEIILHPKYD 134

  Fly   205 TEDEEQGFKNDIALVELDRKAEF-NDHVAAVCLPPDSGNDVQQV-----TAAGWGFTADGVKSSH 263
                ...|.|||||:..||...| :..:..:||.|.....:..|     .|.|:||     ..:|
Mosquito   135 ----RHTFYNDIALMRPDRAISFASFSIFPICLWPTHNATLIDVLSRSGIAVGFGF-----DETH 190

  Fly   264 LLKVNLQRFSDEVCQKR---------LRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYP 319
            .:...||:.|.:|.:|:         :||......:.||....|.|:.|:|||||.::.......
Mosquito   191 RISETLQQASMKVIEKQQCIEQLPEHVRFLPQDAGKMCAIGTESGANVCSGDSGGGLYFAKDQVW 255

  Fly   320 CLKQVIGIVS--------YGLVCGSQGLPSVYTKVHLYTDWIES 355
            .|:   ||||        .|....:..||:.||.|..||.||.:
Mosquito   256 YLR---GIVSAAARRDLDTGEATCNAALPATYTDVAQYTTWINA 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	76/277 (27%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	74/273 (27%)
AgaP_AGAP007043	XP_001237132.2	Tryp_SPc	50..297	CDD:238113	76/274 (28%)
		Tryp_SPc	50..294	CDD:214473	74/270 (27%)
		Tryp_SPc	330..573	CDD:304450
		Tryp_SPc	330..570	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910