DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and tmprss2.15

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_031752206.1	Gene:	tmprss2.15 / 101732233	XenbaseID:	XB-GENE-22065943	Length:	504	Species:	Xenopus tropicalis

Alignment Length:	414	Identity:	110/414 - (26%)
Similarity:	164/414 - (39%)	Gaps:	110/414 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 QILLLIASVSVV-TEYCD------NGTGE--CKEL----------TPSDC---PVIFYNQHLIGA 50
            |:|...:.|.|: :::||      |||.|  |..|          :|:..   ||.:
Frog   128 QMLCGSSGVCVLYSQWCDGIPQCPNGTDEQTCVRLYGPNFQLQAYSPAKATWLPVCY-------- 184

  Fly    51 EVKYCDEFND----IVCCPI----------------------PLDHQNLKPAEQTR-PFEKQCKQ 88
                 ||::|    |.|..|                      .|...|:.....|. .:...|..
Frog   185 -----DEWSDNSGKIACQDIGYSMSSYYQSSQLLASSSNGYFVLQSSNVTGKMYTNLNYSATCAS 244

  Fly    89 YNEVRSACQSTPF-------IVGGTKASGKEFPF----MALIGTHRPNKSKSDINWDCGGSVVHP 142
            .|.|...|.|...       |||||.||..::|:    :.|:||.         .:.||||::.|
Frog   245 GNMVSLRCISCGLSTKVDSRIVGGTPASVGDWPWQVELLKLVGTS---------IYLCGGSIITP 300

  Fly   143 KFVLTAAHCLETDESKAERLDPNFDSPK-FVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTE 206
            .:::|||||:....|          :|. |.|..|.|    |........:.|...:|||.|.:.
Frog   301 HWIVTAAHCVYGSTS----------TPSAFKVFAGSL----TIQSYYSAGYTVERALVHPSYSSY 351

  Fly   207 DEEQGFKNDIALVELDRKAEFNDHVAAVCLPPDSG---NDVQQVTAAGWGFTADGVK-SSHLLKV 267
            .:..    |:||::|.....|..::..||| |:.|   .:.|....:|||.||:|.. |.:|:..
Frog   352 TQIY----DVALLKLTAALVFTTNLRPVCL-PNVGMPWAEGQPCWISGWGTTAEGGSISKNLMAA 411

  Fly   268 NLQRFSDEVC-QKRLRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYG 331
            ::...|...| |..:.....:.|..|||.:|...|||.||||||:..:   ...|..::|..|:|
Frog   412 SVPIISSTTCNQAAVYGGAISSTMMCAGYLSGGTDTCQGDSGGPLVTK---TNSLWWLVGDTSWG 473

  Fly   332 LVCGSQGLPSVYTKVHLYTDWIES 355
            ..|.....|.||..|.::.:||.|
Frog   474 YGCARAYKPGVYGNVTVFIEWIYS 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	81/264 (31%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	78/260 (30%)
tmprss2.15	XP_031752206.1	LDLa	93..121	CDD:238060
		SRCR_2	164..259	CDD:406055	17/107 (16%)
		Tryp_SPc	265..498	CDD:238113	81/264 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910