DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and f12

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_017947702.2	Gene:	f12 / 100493769	XenbaseID:	XB-GENE-1004811	Length:	597	Species:	Xenopus tropicalis

Alignment Length:	313	Identity:	93/313 - (29%)
Similarity:	132/313 - (42%)	Gaps:	76/313 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 PLDHQNLKPAEQTRPFEKQCKQYNEVRSACQSTPFIVGGTKASGKEFPFMALIGTHRPNKSKSDI 131
            |:|.:...|.:..|.|:|          .....|.||||..|.....|::|.:...
Frog   334 PVDGRIDLPVDCGRKFQK----------TPSIMPRIVGGLVALPASHPYIAALYID--------- 379

  Fly   132 NWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGELDYNSTTDDALVQDFRVVN 196
            |..||||::.|.:::||||||:      :|  ||.  .|..|.||:..:| |||...| ...|..
Frog   380 NHFCGGSLISPCWIVTAAHCLD------QR--PNV--TKISVVLGQSRFN-TTDQHTV-TLLVEK 432

  Fly   197 YVVHPGY--DTEDEEQGFKNDIALVELDR-----KAEFNDHVAAVCLPPD--SGNDVQQVTAAGW 252
            |::|..|  ||      .::|||||::..     .:||:..|..:|||..  .....:|...|||
Frog   433 YILHEKYYGDT------LQHDIALVKVKSINGLCASEFSQFVQPICLPQQFKMAESTKQCVVAGW 491

  Fly   253 GFTADGVK--SSHLLKVNLQRFSDEVCQK------RLRFSIDTRTQFCAGSMSSQADTCNGDSGG 309
            |...:|.:  :..|.:.::.......||.      |:     .....|||.|....|.|.|||||
Frog   492 GHQYEGAEHYAFFLQEASMPIIPYTQCQSPSVHGDRM-----LPGMLCAGFMEGGVDACQGDSGG 551

  Fly   310 PIFVQ-------HPLYPCLKQVIGIVSYGLVCGSQGLPSVYTKVHLYTDWIES 355
            |:..:       |          |:||:|..|..:..|.|||.|..|||||.:
Frog   552 PLVCEVDGRIELH----------GVVSWGSGCAEENKPGVYTAVTSYTDWIRA 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	86/278 (31%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	84/274 (31%)
f12	XP_017947702.2	fn2	46..87	CDD:394995
		EGF_CA	95..129	CDD:238011
		KR	213..298	CDD:214527
		Tryp_SPc	359..595	CDD:238113	86/278 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910