DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and tmprss15

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_031752048.1	Gene:	tmprss15 / 100490249	XenbaseID:	XB-GENE-999987	Length:	994	Species:	Xenopus tropicalis

Alignment Length:	390	Identity:	98/390 - (25%)
Similarity:	163/390 - (41%)	Gaps:	96/390 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 CDNGTGE--CKELTPSDCPVIFYNQHLIG-AEVKYCDEF-------------NDIVCCPIPLDHQ 71
            ||:||.|  |..|         :|..:.| .:.|...|:             ||| |..:.|.:.
Frog   645 CDDGTDERHCVRL---------FNSSMSGLVQFKVQSEWHTACIDHWNEDISNDI-CHRLGLGNV 699

  Fly    72 NLKPA---EQTRPF---------------EKQCKQYNEVRSACQ------------STPFIVGGT 106
            ||..|   |...||               ..||...:.:...||            |...||||:
Frog   700 NLTSAVLSEGNGPFVTLIQVEDGSLSLLPSDQCANQSVIHIQCQQRECGKRLVPIKSGSKIVGGS 764

  Fly   107 KASGKEFPFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKF 171
            .|:...:|:  ::..:..::.      .||.|:|:.:::::||||:     ....|.|:    .:
Frog   765 DAALGAWPW--IVSLYYNDRQ------TCGASLVNQEWLVSAAHCV-----YGRNLIPS----NW 812

  Fly   172 VVRLG-ELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVC 235
            ..||| ..:.|.|......|  .:...|::|.|:...::    :||.::.|..|..::|::..:|
Frog   813 KARLGLHTNLNLTQPQIATQ--MIDQIVINPQYNRRTKD----SDIVMMHLQFKVNYSDYIQPIC 871

  Fly   236 LP-PDSGNDVQ-QVTAAGWGFTADGVKSSHLL-KVNLQRFSDEVCQKRL-RFSIDTRTQFCAGSM 296
            || .|....|. ..:.||||.|..|....::| :..:...|:..||::: .::| |....|.|..
Frog   872 LPETDQEFSVGINCSIAGWGRTQSGGPVPNILQEAEIPLISNHKCQQQMPEYNI-TDNMVCGGYE 935

  Fly   297 SSQADTCNGDSGGPIFVQHPLYPCLKQ----VIGIVSYGLVCGSQGLPSVYTKVHLYTDWIESIV 357
            ....|||.||||||:.       |.:.    ::|:.|:|..|.....|.||.:|..:|:||:|.:
Frog   936 EGGIDTCQGDSGGPMM-------CQQNNEWFLVGVTSFGYGCAQPSRPGVYVRVTEFTNWIKSFI 993

Fly 358 357
Frog 994 993

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	70/262 (27%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	68/259 (26%)
tmprss15	XP_031752048.1	SEA	36..>103	CDD:396113
		LDLa	157..190	CDD:197566
		CUB	199..305	CDD:238001
		MAM	321..478	CDD:395504
		CUB	501..608	CDD:395345
		LDLa	620..654	CDD:238060	5/8 (63%)
		SR	655..746	CDD:214555	20/100 (20%)
		Tryp_SPc	760..991	CDD:238113	70/261 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910