DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and klkb1

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_002934450.3	Gene:	klkb1 / 100486524	XenbaseID:	XB-GENE-985051	Length:	629	Species:	Xenopus tropicalis

Alignment Length:	380	Identity:	103/380 - (27%)
Similarity:	158/380 - (41%)	Gaps:	95/380 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 CKELTPSDCPVI------FYNQHLIGAEV---KYCDE--FNDIVCCPIPLDHQNLKPAEQTRPFE 83
            || .:||.||:.      |....|:..||   |.|.:  .|:|.|     .....:|. |:...|
Frog   283 CK-FSPSVCPLTILSDAEFLGDELLVEEVSGEKECQQECTNNIRC-----QFFTYRPM-QSGCSE 340

  Fly    84 KQCKQYNEVRS--------------------ACQ-------STPF-----IVGGTKASGKEFPF- 115
            .:||.:.::.|                    .|:       ..|.     |||||.:...|:|:
Frog   341 NKCKCHMKISSNGLPTGIRHGNGEISGFSLRLCKIKSVKGCGEPIEHANRIVGGTDSVLGEWPWQ 405

  Fly   116 ----MALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPK-FVVRL 175
                :.|..:::.:.        ||||::..::::|||||.        .:.|   .|: :::..
Frog   406 VSMHLRLTASYKKHA--------CGGSIISNQWIVTAAHCF--------AMHP---LPQMWIIYS 451

  Fly   176 GELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCLPPDS 240
            |.:..::.|......:...:  ::||.|    ...|...||||::|.....||||..|:||||..
Frog   452 GVVKLSNITQSTPFSETEQI--IIHPHY----TGAGNGTDIALLKLKTPISFNDHQKAICLPPRE 510

  Fly   241 GNDV--QQVTAAGWGFTAD-GVKSSHLLKVNLQRFSDEVCQKRLRFSIDTRTQFCAGSMSSQADT 302
            ...|  ......|||||.: |..::.|.|..:.:.|.|.||.....:...:...|||....:.|:
Frog   511 PTFVLPNSCWITGWGFTEESGSLANILQKAEVPQISTEECQGNYEQTRIDKKILCAGYKRGKIDS 575

  Fly   303 CNGDSGGPIFVQHPLYPCLKQVI----GIVSYGLVCGSQGLPSVYTKVHLYTDWI 353
            |.||||||:       .|:...|    ||.|:|..|...|.|.|||:|..:||||
Frog   576 CKGDSGGPL-------ACVVDEIWYLTGITSWGEGCARPGKPGVYTRVSEFTDWI 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	80/265 (30%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	78/263 (30%)
klkb1	XP_002934450.3	APPLE	21..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519	103/380 (27%)
		APPLE	290..373	CDD:128519	17/88 (19%)
		Tryp_SPc	391..626	CDD:238113	80/265 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910