DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and hgfac

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_002939269.3	Gene:	hgfac / 100485696	XenbaseID:	XB-GENE-940012	Length:	595	Species:	Xenopus tropicalis

Alignment Length:	336	Identity:	101/336 - (30%)
Similarity:	140/336 - (41%)	Gaps:	78/336 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 EVKYCDEFNDIVC----CPIP----LDHQNLKPAEQTRPFEKQCKQYNEVRSACQSTPFIVGGTK 107
            |:.:|...||.:.    |.||    ...:.:...:...|...:|.:.:|.|...:..  |:||..
Frog   295 EIPWCYLMNDRLVSWEHCSIPKCRDKGRRVIMQEDAVVPAPPKCGKKHEKRVVARGR--ILGGNS 357

  Fly   108 ASGKEFPFMA--LIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPK 170
            |.....|::|  .||           |:.|.||::.|.:|::||||.....||:          |
Frog   358 ALPGSHPWVAGIYIG-----------NYFCAGSLIQPCWVVSAAHCFADSPSKS----------K 401

  Fly   171 FVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFK---NDIALVELDR-------KA 225
            ..|.||:..:|.|||  :.|.|.|..|:.:..|..      ||   :||.|::|.|       |.
Frog   402 IRVVLGQHFFNQTTD--VTQTFEVERYIFYDKYSV------FKRNEHDIVLIKLKRINNACAKKT 458

  Fly   226 EFNDHVAAVCLPPDSG--NDVQQVTAAGWG-FTADGVKSSHLLKVNLQR-----FSDEVCQKRLR 282
            :|   |..:|||..|.  .|......|||| ...|..:.:.    |||.     ..|..|.....
Frog   459 QF---VQTICLPDVSAPFADDHHCQIAGWGRMHEDSTEYAQ----NLQEAIVPLVPDNKCSSPEI 516

  Fly   283 FSID-TRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVI----GIVSYGLVCGSQGLPSV 342
            :..: :...||||......|:|.||||||:       .|.|..|    ||||:|..||:...|.|
Frog   517 YGAEISENMFCAGYFDCTIDSCQGDSGGPL-------ACEKDKISYLWGIVSWGEGCGNHNKPGV 574

  Fly   343 YTKVHLYTDWI 353
            ||||..|.|||
Frog   575 YTKVSNYVDWI 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	90/277 (32%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	88/275 (32%)
hgfac	XP_002939269.3	FN2	52..98	CDD:238019
		EGF_CA	109..145	CDD:238011
		FN1	147..185	CDD:238018
		KR	235..319	CDD:294073	7/23 (30%)
		Tryp_SPc	351..585	CDD:214473	88/278 (32%)
		Tryp_SPc	352..588	CDD:238113	90/277 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910