DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and tmprss15

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_001919639.2	Gene:	tmprss15 / 100148042	ZFINID:	ZDB-GENE-091204-83	Length:	990	Species:	Danio rerio

Alignment Length:	403	Identity:	97/403 - (24%)
Similarity:	151/403 - (37%)	Gaps:	100/403 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ASVSVVTEYCDNGTGECKELTPSDCPVIFYNQHLIGAE---------------VKYCDEFNDIVC 63
            |||....|.|.|||.|      :|| |.....:..|.|               ..:..:|:|..|
Zfish   612 ASVCDGVEDCPNGTDE------ADC-VHVIKDNTTGTERLKLRIQNNLYTVCAQDWTPQFSDFFC 669

  Fly    64 -------------------CPIPLDHQNLKPAEQTRPFEKQCKQYNEVRSACQSTPF-------- 101
                               .|....:.|...:.:.:|.:| |.....|...|.:.|.
Zfish   670 RYLGYRSGVALFSITVEGDGPFTTVNVNTNGSLELKPSDK-CISEKIVSLHCNNQPCGVRKVPSK 733

  Fly   102 --------------IVGGTKASGKEFPFMA---LIGTHRPNKSKSDINWDCGGSVVHPKFVLTAA 149
                          :|||..|....:|:|.   .:|.|.           ||.:::..::::|||
Zfish   734 SKIIEETDGKKEGRVVGGQDAQRGAWPWMVSLQWLGGHA-----------CGATLIDREWLITAA 787

  Fly   150 HCLETDESKAERLDPNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKN 214
            ||:         ...|.....:...|| |.....|.:...|.|.|...::|..|:...:|    :
Zfish   788 HCV---------YGRNVQLSNWAAVLG-LHAQFETINPNKQVFSVDQVIMHKHYNKRTKE----S 838

  Fly   215 DIALVELDRKAEFNDHVAAVCLPPDSG---NDVQQVTAAGWGFTAD-GVKSSHLLKVNLQRFSDE 275
            |.||:.|.....:.|:|..:|| ||.|   .:.::...||||..:: |:|:..|.:..:...|:.
Zfish   839 DFALMHLKTPVSYTDYVQPICL-PDPGAHFEEGRKCFIAGWGLLSESGLKADVLQQAVVPLLSNT 902

  Fly   276 VCQKRLRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLVCGSQGLP 340
            .||:.|.....|....|||......|||.||||||:..:...:..|   :|..|:|:.||....|
Zfish   903 QCQEWLPEYNFTERMMCAGYAEGGVDTCQGDSGGPLMCEEEGHWVL---VGATSFGIGCGRPQRP 964

  Fly   341 SVYTKVHLYTDWI 353
            ..|.:|..:.||:
Zfish   965 GAYARVSQFVDWV 977

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	72/259 (28%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	71/257 (28%)
tmprss15	XP_001919639.2	SEA	19..>89	CDD:279699
		LDLa	142..175	CDD:238060
		CUB	183..288	CDD:238001
		MAM	302..457	CDD:279023
		MAM	302..457	CDD:99706
		CUB	477..586	CDD:238001
		LDLa	596..630	CDD:238060	9/23 (39%)
		SRCR_2	653..728	CDD:295335	11/75 (15%)
		Tryp_SPc	747..977	CDD:214473	71/258 (28%)
		Tryp_SPc	748..980	CDD:238113	72/259 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910