DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and LOC100004411

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_001343728.4	Gene:	LOC100004411 / 100004411	-ID:	-	Length:	494	Species:	Danio rerio

Alignment Length:	422	Identity:	109/422 - (25%)
Similarity:	154/422 - (36%)	Gaps:	130/422 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 CDNGTGECKE-------LTP------------SDCPVIFYNQHLIGAEVKYC--DEFNDIVC-C- 64
            |.|| |.|:|       |.|            |||      ::..|..:.||  :|...:.| |
Zfish    95 CQNG-GMCRENRGVQECLCPPLYSGTNCETEVSDC------KYKNGGCLHYCSQNETAGVECSCA 152

  Fly    65 ---PIPLDHQNLKPAEQTRPFEKQ------CKQYNEV------------------------RSAC 96
               .:..|..:..||.| .|..||      .:..::|                        |||.
Zfish   153 DGYQLDEDRHSCSPAVQ-YPCGKQWTGGIMSRSLDDVSHTHADYANHTHSSTSPSHPLHHNRSAL 216

  Fly    97 QSTPF---------------------------IVGGTKASGKEFPFMALIGTHRPNKSKSDINWD 134
            :::..                           ||||........|:..|:       .:.|....
Zfish   217 ENSTHQNQTELTAPDQLLDTGSDFTGGNEDTRIVGGQLQRQGGSPWQVLL-------RREDEYGF 274

  Fly   135 CGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKFVVRLGELDYNSTTDDALVQDFRVVNYVV 199
            ||||:::.::|:||||||:             .:|..:. :|  ||:....|...|...|...:.
Zfish   275 CGGSLINQRWVITAAHCLQ-------------QTPHHIT-IG--DYDKMRPDKDEQKITVEKIIP 323

  Fly   200 HPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCLPPDSG------NDVQQVTAAGWGFTADG 258
            ||.|    .|..|.:||||:.|..........:..|| ||:.      ...:|...:|||.|...
Zfish   324 HPHY----HEYTFDSDIALLYLSSAVTLGPFASPACL-PDANLAERLMKPGEQGLVSGWGSTHYL 383

  Fly   259 VKSSHLL-KVNLQRFSDEVCQKRLRFSIDTRTQFCAGSMSSQADTCNGDSGGPIFVQHPLYPCLK 322
            .:||..| ||.|.....:.|..... .|.|...||||.:..:.|.|.||||||..|.   |....
Zfish   384 QRSSRFLRKVQLPVVEQKSCINSTE-QIITDNMFCAGFLMEEMDACTGDSGGPFIVN---YRGTW 444

  Fly   323 QVIGIVSYGLVCGSQGLPSVYTKVHLYTDWIE 354
            .:.|:||:|..|.|||...|||::..|..||:
Zfish   445 FLTGVVSWGERCASQGKYGVYTRLGNYLSWIQ 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	81/260 (31%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	79/257 (31%)
LOC100004411	XP_001343728.4	GLA	22..85	CDD:214503
		EGF_CA	86..122	CDD:238011	8/27 (30%)
		FXa_inhibition	128..164	CDD:291342	8/41 (20%)
		Tryp_SPc	248..475	CDD:214473	79/258 (31%)
		Tryp_SPc	249..477	CDD:238113	81/260 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910