DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3700 and tmprss3a

DIOPT Version :9

Sequence 1:	NP_611736.1	Gene:	CG3700 / 37640	FlyBaseID:	FBgn0034796	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	379	Identity:	98/379 - (25%)
Similarity:	155/379 - (40%)	Gaps:	81/379 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 IASVSVVTEYCDNGTGE--CKE-----LTPSDCPVIFYNQHLIGAEVKYCDEFNDIVCCPIPLDH 70
            ::..|.|.:..::|...  |.|     |:.|.|..:.|::.:         |...:....|..|:
Zfish   189 LSGKSSVLQVLNDGVWRTVCAENWNSNLSLSACKQLGYSRFV---------ESKALPLSFIEQDY 244

  Fly    71 QN--LKPAEQTRPFEKQCKQYNEVRS----------------ACQSTP----FIVGGTKASGKEF 113
            ||  :........|::..|.:|...|                ||.|.|    .||||..::..:|
Zfish   245 QNNLISIGLNQTSFQQPVKIHNITNSSKTKCSLGMVTALKCIACGSRPKFSARIVGGNLSAEGQF 309

  Fly   114 PFMALIGTHRPNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPKF---VVRL 175
            |:.  :..|..|:..      ||||::..:::||||||:.           ....|.:   ...|
Zfish   310 PWQ--VSLHFQNEHL------CGGSIITSRWILTAAHCVY-----------GIAYPMYWMVYAGL 355

  Fly   176 GELDYNSTTDDALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRKAEFNDHVAAVCLP--P 238
            .||..|:      |:.|.|...:.|..|    ..:|..:||||::|.:...||..|..:|||  .
Zfish   356 TELPLNA------VKAFAVEKIIYHSRY----RPKGLDHDIALMKLAQPLTFNGMVEPICLPNFG 410

  Fly   239 DSGNDVQQVTAAGWGFTADGVKSS---HLLKVNLQRFSDEVC-QKRLRFSIDTRTQFCAGSMSSQ 299
            :...|.:....:|||.|.||..:|   |...|.|  .|::.| |..:.....|....|||.:...
Zfish   411 EQFEDGKMCWISGWGATEDGGDASVSQHCASVPL--ISNKACSQPEVYQGYLTAGMICAGYLDGG 473

  Fly   300 ADTCNGDSGGPIFVQHPLYPCLKQVIGIVSYGLVCGSQGLPSVYTKVHLYTDWI 353
            .|:|.||||||:..:.   ..:.:::|..|:|..|..:..|.|||::.....||
Zfish   474 TDSCQGDSGGPLACED---SSIWKLVGATSWGQGCAEKNKPGVYTRITQSLTWI 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	76/261 (29%)
CG3700	NP_611736.1	Tryp_SPc	102..353	CDD:214473	74/259 (29%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845	21/109 (19%)
		Tryp_SPc	298..525	CDD:238113	76/261 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910