Protein Alignment Gmer and SDR42E1

DIOPT Version :10

• Sequence 1: NP_611734.1
• Gene: Gmer / 37638
• FlyBaseID: FBgn0267823
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_660151.2
• Gene: SDR42E1 / 93517
• HGNCID: 29834
• Length: 393
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 62/273 - (22%)
• Similarity: 101/273 - (36%)
• Gaps: 59/273 - (21%)

  Fly     2 KKVLVTGGTGLVGKALEAVIKE----------QSPEDEQWFFAGSK--DADLTNLAATQALFARE 54
            :.||:|||:|..|..|...:.:          .||  .|....|.|  ..|:.:|:..:..|...
Human     9 ESVLITGGSGYFGFRLGCALNQNGVHVILFDISSP--AQTIPEGIKFIQGDIRHLSDVEKAFQDA 71

  Fly    55 KPTHVIHLAAMVGGLFHNMNNNLDFLRNNLLINDNVLQTAHEQGCVKVV-SCLSTCIFPDKTSYP 118
            ..|.|.|:|:........:|.|| ....|:...||:||....:...::| :.....||..:....
Human    72 DVTCVFHIASYGMSGREQLNRNL-IKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIFGGQVIRN 135

  Fly   119 IDETM----VHNGPPHPSNYGYSYAKRLIDVQ----NHAYHDK-YGRVYTSVI-PCNIFGP-HDN 172
            .||::    :|..|.|     ||..|.:.:.:    |....|: .|.:.|..: |..|:|| ...
Human   136 GDESLPYLPLHLHPDH-----YSRTKSIAEQKVLEANATPLDRGDGVLRTCALRPAGIYGPGEQR 195

  Fly   173 YNPE-VSHVIPGM-------------------IYRMHQLVTE-----KTDVPENDKVFTVFGSGM 212
            :.|. ||::..|:                   :.:.|.|.:|     |..:......|  ...|.
Human   196 HLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRADKGHIASGQPYF--ISDGR 258

  Fly   213 PLRQFVYSRDLAE 225
            |:..|.:.|.|.|
Human   259 PVNNFEFFRPLVE 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gmer	NP_611734.1	GDP_FS_SDR_e	3..313	CDD:187550	62/272 (23%)
SDR42E1	NP_660151.2	3b-HSD_like_1_SDR_e	10..350	CDD:187672	62/272 (23%)