Protein Alignment Gmer and SDR42E1

DIOPT Version :9

• Sequence 1: NP_611734.1
• Gene: Gmer / 37638
• FlyBaseID: FBgn0267823
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_660151.2
• Gene: SDR42E1 / 93517
• HGNCID: 29834
• Length: 393
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 62/273 - (22%)
• Similarity: 101/273 - (36%)
• Gaps: 59/273 - (21%)

  Fly     2 KKVLVTGGTGLVGKALEAVIKE----------QSPEDEQWFFAGSK--DADLTNLAATQALFARE 54
            :.||:|||:|..|..|...:.:          .||  .|....|.|  ..|:.:|:..:..|...
Human     9 ESVLITGGSGYFGFRLGCALNQNGVHVILFDISSP--AQTIPEGIKFIQGDIRHLSDVEKAFQDA 71

  Fly    55 KPTHVIHLAAMVGGLFHNMNNNLDFLRNNLLINDNVLQTAHEQGCVKVV-SCLSTCIFPDKTSYP 118
            ..|.|.|:|:........:|.|| ....|:...||:||....:...::| :.....||..:....
Human    72 DVTCVFHIASYGMSGREQLNRNL-IKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIFGGQVIRN 135

  Fly   119 IDETM----VHNGPPHPSNYGYSYAKRLIDVQ----NHAYHDK-YGRVYTSVI-PCNIFGP-HDN 172
            .||::    :|..|.|     ||..|.:.:.:    |....|: .|.:.|..: |..|:|| ...
Human   136 GDESLPYLPLHLHPDH-----YSRTKSIAEQKVLEANATPLDRGDGVLRTCALRPAGIYGPGEQR 195

  Fly   173 YNPE-VSHVIPGM-------------------IYRMHQLVTE-----KTDVPENDKVFTVFGSGM 212
            :.|. ||::..|:                   :.:.|.|.:|     |..:......|  ...|.
Human   196 HLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRADKGHIASGQPYF--ISDGR 258

  Fly   213 PLRQFVYSRDLAE 225
            |:..|.:.|.|.|
Human   259 PVNNFEFFRPLVE 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gmer	NP_611734.1	GDP_FS_SDR_e	3..313	CDD:187550	62/272 (23%)
		Epimerase	4..234	CDD:279681	62/271 (23%)
SDR42E1	NP_660151.2	3b-HSD_like_1_SDR_e	10..350	CDD:187672	62/272 (23%)
		3Beta_HSD	12..283	CDD:279420	61/270 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0451
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900