Protein Alignment Gmer and ERG26

DIOPT Version :10

• Sequence 1: NP_611734.1
• Gene: Gmer / 37638
• FlyBaseID: FBgn0267823
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_011514.1
• Gene: ERG26 / 852883
• SGDID: S000002969
• Length: 349
• Species: Saccharomyces cerevisiae
• Alignment Length: 384
• Identity: 76/384 - (19%)
• Similarity: 132/384 - (34%)
• Gaps: 116/384 - (30%)

  Fly     4 VLVTGGTGLVGKALEAVIKEQSPE-----------------------DEQWFFAGSKDADLTNLA 45
            ||:.||:|.:|..|.....:.:|:                       |:..|..|    |||:..
Yeast     7 VLIIGGSGFLGLHLIQQFFDINPKPDIHIFDVRDLPEKLSKQFTFNVDDIKFHKG----DLTSPD 67

  Fly    46 ATQALFAREKPTHVIHLAAMVGGLFHNMNNNL-DFLRNNLLINDNVLQTAHEQGC-VKVVSCLST 108
            ..:......|...|:|.|:.:    |..|.:: |.:  |:....||:....:.|. :.|.:..:.
Yeast    68 DMENAINESKANVVVHCASPM----HGQNPDIYDIV--NVKGTRNVIDMCKKCGVNILVYTSSAG 126

  Fly   109 CIFPDKTSYPIDETMVHNGP-PHPSNYGYSYAKRLIDVQNHAYHDKYGRVYTSVI-PCNIFGPHD 171
            .||..:..:..|||.    | |......|:..|.:.:......:|.....||..: |..||||.|
Yeast   127 VIFNGQDVHNADETW----PIPEVPMDAYNETKAIAEDMVLKANDPSSDFYTVALRPAGIFGPGD 187

  Fly   172 NYNPEVSHVIPGMIYRMHQLVTEKTDVPENDKVFTVFGSGMPLRQFVYSRDLAELMIWVLRNYES 236
            .      .::|| :.::.:|...|..:.:|:.:|          .:.|:.::|:  ..||...:.
Yeast   188 R------QLVPG-LRQVAKLGQSKFQIGDNNNLF----------DWTYAGNVAD--AHVLAAQKL 233

  Fly   237 VEPIILSADEVQEVTIF----------EVAQAVAKAFN--------------------------- 264
            ::|...:|  |...|.|          .:|:.|.||..
Yeast   234 LDPKTRTA--VSGETFFITNDTPTYFWALARTVWKADGHIDKHVIVLKRPVAICAGYLSEWVSKM 296

  Fly   265 ---------FNGRLVCDTSKSDGQYKKTASNAKLRSFLPDYAFTDLETAINASVKWYIE 314
                     |..::||..     :|...|...||..:.|.   ..:|..||.::.|..|
Yeast   297 LGKEPGLTPFRVKIVCAY-----RYHNIAKAKKLLGYTPR---VGIEEGINKTLAWMDE 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gmer	NP_611734.1	GDP_FS_SDR_e	3..313	CDD:187550	75/381 (20%)
ERG26	NP_011514.1	3b-HSD-NSDHL-like_SDR_e	6..345	CDD:187673	74/380 (19%)