Protein Alignment Gmer and HSD3B7

DIOPT Version :9

• Sequence 1: NP_611734.1
• Gene: Gmer / 37638
• FlyBaseID: FBgn0267823
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_079469.2
• Gene: HSD3B7 / 80270
• HGNCID: 18324
• Length: 369
• Species: Homo sapiens
• Alignment Length: 412
• Identity: 80/412 - (19%)
• Similarity: 128/412 - (31%)
• Gaps: 169/412 - (41%)

  Fly     5 LVTGGTGLVGKALEAVIKEQSPE-------DEQ---WF--------FAGSKDADLTNLAATQALF 51
            |||||.|.:|:.:..::.::.|.       |:.   |.        ...:...|:|......|..
Human    13 LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTAIQGDVTQAHEVAAAV 77

  Fly    52 AREKPTH-VIHLAAMVGGLFHNMNNNLDFLRNNLLINDNVLQTAHE---QGCVKVV-SCLST--- 108
            |   ..| |||.|.:| .:|...:.                :|.||   ||...|: :|:.|
Human    78 A---GAHVVIHTAGLV-DVFGRASP----------------KTIHEVNVQGTRNVIEACVQTGTR 122

  Fly   109 ---------CIFPDKTSYPI----DET---MVHNGPPHPSNYGYSYAKRLIDVQNHAYHDKYGR- 156
                     .:.|:...:|.    ::|   .||.   ||.....:.|:.|:...|       ||
Human   123 FLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHR---HPYPCSKALAEWLVLEAN-------GRK 177

  Fly   157 -------VYTSVIPCNIFGP-----HDNYN--------------PEVSH--VIPGMIYRMHQLVT 193
                   |..::.|..|:|.     .|.|.              ..|.|  |..|.:..||.|..
Human   178 VRGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVLAA 242

  Fly   194 EKTDVPENDKVFTVFG-------SGMPLRQF---------------------------VYSRDLA 224
            .     |.::..|:.|       .|.|.|.:                           |:...|.
Human   243 R-----ELEQRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLLVFLAALN 302

  Fly   225 ELMIWVLRNYESVEPIILSADEVQEVTIFEVAQAVAKAFNFNGRLVCDTSKSDGQYKKTASNAKL 289
            .|:.|:||      |::|.|..:...|:     |||     |......|.|:...:
Human   303 ALLQWLLR------PLVLYAPLLNPYTL-----AVA-----NTTFTVSTDKAQRHF--------- 342

  Fly   290 RSFLPDYAFTDLETAINASVKW 311
             .:.|.:::.|..|   .::.|
Human   343 -GYEPLFSWEDSRT---RTILW 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gmer	NP_611734.1	GDP_FS_SDR_e	3..313	CDD:187550	80/412 (19%)
		Epimerase	4..234	CDD:279681	66/333 (20%)
HSD3B7	NP_079469.2	3b-HSD_HSDB1_like_SDR_e	11..361	CDD:187671	80/412 (19%)
		3Beta_HSD	13..291	CDD:279420	60/312 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0451
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900