Protein Alignment Gmer and UXS1

DIOPT Version :10

• Sequence 1: NP_611734.1
• Gene: Gmer / 37638
• FlyBaseID: FBgn0267823
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_001240804.1
• Gene: UXS1 / 80146
• HGNCID: 17729
• Length: 425
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 75/331 - (22%)
• Similarity: 125/331 - (37%)
• Gaps: 48/331 - (14%)

  Fly     2 KKVLVTGGTGLVGKAL---------EAVIKE-----QSPEDEQWFFAGSKDADLTNLAATQALFA 52
            |::|:|||.|.||..|         |..:.:     :....|.|.  |.::.:|.|....:.|:.
Human    94 KRILITGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRKRNVEHWI--GHENFELINHDVVEPLYI 156

  Fly    53 REKPTHVIHLAAMVGGLFHNMNNNLDFLRNNLLINDNVLQTAHEQGCVKVVSCLSTCIFPDKTSY 117
              :...:.|||:..... :.|.|.:..|:.|.:...|:|..|...|...:::..|. ::.|...:
Human   157 --EVDQIYHLASPASPP-NYMYNPIKTLKTNTIGTLNMLGLAKRVGARLLLASTSE-VYGDPEVH 217

  Fly   118 PIDETMVHNGPPHPSNYGYSYAKRLIDVQNHAYHDKYG------RVYTSVIPCNIFGPHDNYNPE 176
            |..|....:..|......|...||:.:...:||..:.|      |::      |.|||..:.|.
Human   218 PQSEDYWGHVNPIGPRACYDEGKRVAETMCYAYMKQEGVEVRVARIF------NTFGPRMHMND- 275

  Fly   177 VSHVIPGMIYRMHQLVTEKTDVPENDKVFTVFGSGMPLRQFVYSRDLAELMIWVLRNYESVEPII 241
             ..|:...|.:..|           .:..||:|||...|.|.|..||...:: .|.|.....|:.
Human   276 -GRVVSNFILQALQ-----------GEPLTVYGSGSQTRAFQYVSDLVNGLV-ALMNSNVSSPVN 327

  Fly   242 LSADEVQEVTIFEVAQAVAKAFNFNGRLVCDTSKSDGQYKKTASNAKLRSFLPDYAFTDLETAIN 306
            |...|  |.||.|.||.:.........:...:...|...|:.....|.:..|.......||..:|
Human   328 LGNPE--EHTILEFAQLIKNLVGSGSEIQFLSEAQDDPQKRKPDIKKAKLMLGWEPVVPLEEGLN 390

  Fly   307 ASVKWY 312
            .::.::
Human   391 KAIHYF 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gmer	NP_611734.1	GDP_FS_SDR_e	3..313	CDD:187550	74/330 (22%)
UXS1	NP_001240804.1	UXS1_N	4..83	CDD:463356
		UGD_SDR_e	94..397	CDD:187541	75/331 (23%)