DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gmer and UXS1

DIOPT Version :9

Sequence 1:NP_611734.1 Gene:Gmer / 37638 FlyBaseID:FBgn0267823 Length:321 Species:Drosophila melanogaster
Sequence 2:NP_001240804.1 Gene:UXS1 / 80146 HGNCID:17729 Length:425 Species:Homo sapiens


Alignment Length:331 Identity:75/331 - (22%)
Similarity:125/331 - (37%) Gaps:48/331 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 KKVLVTGGTGLVGKAL---------EAVIKE-----QSPEDEQWFFAGSKDADLTNLAATQALFA 52
            |::|:|||.|.||..|         |..:.:     :....|.|.  |.::.:|.|....:.|:.
Human    94 KRILITGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRKRNVEHWI--GHENFELINHDVVEPLYI 156

  Fly    53 REKPTHVIHLAAMVGGLFHNMNNNLDFLRNNLLINDNVLQTAHEQGCVKVVSCLSTCIFPDKTSY 117
              :...:.|||:..... :.|.|.:..|:.|.:...|:|..|...|...:::..|. ::.|...:
Human   157 --EVDQIYHLASPASPP-NYMYNPIKTLKTNTIGTLNMLGLAKRVGARLLLASTSE-VYGDPEVH 217

  Fly   118 PIDETMVHNGPPHPSNYGYSYAKRLIDVQNHAYHDKYG------RVYTSVIPCNIFGPHDNYNPE 176
            |..|....:..|......|...||:.:...:||..:.|      |::      |.|||..:.|. 
Human   218 PQSEDYWGHVNPIGPRACYDEGKRVAETMCYAYMKQEGVEVRVARIF------NTFGPRMHMND- 275

  Fly   177 VSHVIPGMIYRMHQLVTEKTDVPENDKVFTVFGSGMPLRQFVYSRDLAELMIWVLRNYESVEPII 241
             ..|:...|.:..|           .:..||:|||...|.|.|..||...:: .|.|.....|:.
Human   276 -GRVVSNFILQALQ-----------GEPLTVYGSGSQTRAFQYVSDLVNGLV-ALMNSNVSSPVN 327

  Fly   242 LSADEVQEVTIFEVAQAVAKAFNFNGRLVCDTSKSDGQYKKTASNAKLRSFLPDYAFTDLETAIN 306
            |...|  |.||.|.||.:.........:...:...|...|:.....|.:..|.......||..:|
Human   328 LGNPE--EHTILEFAQLIKNLVGSGSEIQFLSEAQDDPQKRKPDIKKAKLMLGWEPVVPLEEGLN 390

  Fly   307 ASVKWY 312
            .::.::
Human   391 KAIHYF 396

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GmerNP_611734.1 GDP_FS_SDR_e 3..313 CDD:187550 74/330 (22%)
Epimerase 4..234 CDD:279681 57/249 (23%)
UXS1NP_001240804.1 UXS1_N 4..83 CDD:288636
WcaG 94..401 CDD:223528 75/331 (23%)
UGD_SDR_e 94..397 CDD:187541 75/331 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0451
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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