Protein Alignment Gmer and GFUS

DIOPT Version :10

• Sequence 1: NP_611734.1
• Gene: Gmer / 37638
• FlyBaseID: FBgn0267823
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_001400338.1
• Gene: GFUS / 7264
• HGNCID: 12390
• Length: 366
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 171/293 - (58%)
• Similarity: 216/293 - (73%)
• Gaps: 9/293 - (3%)

  Fly    31 WFFAGSKD--ADLTNLAATQALFAREKPTHVIHLAAMVGGLFHNMNNNLDFLRNNLLINDNVLQT 93
            ||.....|  |...:.|.|:|||.:.:|||||||||||||||.|:..||||.|.|:.:|||||.:
Human    81 WFPPEPPDSLASYRDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHS 145

  Fly    94 AHEQGCVKVVSCLSTCIFPDKTSYPIDETMVHNGPPHPSNYGYSYAKRLIDVQNHAYHDKYGRVY 158
            |.|.|..|||||||||||||||:|||||||:||||||.||:|||||||:|||||.||..:||..:
Human   146 AFEVGARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTF 210

  Fly   159 TSVIPCNIFGPHDNYNPEVSHVIPGMIYRMHQLVTEKTDVPENDKVFTVFGSGMPLRQFVYSRDL 223
            |:|||.|:||||||:|.|..||:||:|:::|.       ...:....||:|:|.|.|||:||.||
Human   211 TAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHL-------AKSSGSALTVWGTGNPRRQFIYSLDL 268

  Fly   224 AELMIWVLRNYESVEPIILSADEVQEVTIFEVAQAVAKAFNFNGRLVCDTSKSDGQYKKTASNAK 288
            |:|.|||||.|..|||||||..|..||:|.|.|:||.:|.:|:|.:..||:|||||:||||||:|
Human   269 AQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSK 333

  Fly   289 LRSFLPDYAFTDLETAINASVKWYIENYDQARK 321
            ||::|||:.||..:.|:..:..|:.:||:||||
Human   334 LRTYLPDFRFTPFKQAVKETCAWFTDNYEQARK 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gmer	NP_611734.1	GDP_FS_SDR_e	3..313	CDD:187550	165/283 (58%)
GFUS	NP_001400338.1	GDP_FS_SDR_e	94..357	CDD:187550	160/269 (59%)