DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gmer and gfus.3

DIOPT Version :9

Sequence 1:	NP_611734.1	Gene:	Gmer / 37638	FlyBaseID:	FBgn0267823	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001070752.2	Gene:	gfus.3 / 550486	ZFINID:	ZDB-GENE-050417-317	Length:	344	Species:	Danio rerio

Alignment Length:	319	Identity:	189/319 - (59%)
Similarity:	237/319 - (74%)	Gaps:	7/319 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KVLVTGGTGLVGKALEAVIKEQSPEDEQWFFAGSKDADLTNLAATQALFAREKPTHVIHLAAMVG 67
            :||||||:||||:|:|.|:||:....|:|.|..||:|:|.:...|:|:|.:.:||||||||||||
Zfish    33 RVLVTGGSGLVGRAIERVVKEEGRGGEEWTFLSSKEANLLSAKETRAIFEKYRPTHVIHLAAMVG 97

  Fly    68 GLFHNMNNNLDFLRNNLLINDNVLQTAHEQGCVKVVSCLSTCIFPDKTSYPIDETMVHNGPPHPS 132
            |||.||..||||.|||:.|||||||||:|.|.||||||||||||||||:|||||||:||||||.|
Zfish    98 GLFRNMRQNLDFWRNNVFINDNVLQTANEFGVVKVVSCLSTCIFPDKTTYPIDETMIHNGPPHDS 162

  Fly   133 NYGYSYAKRLIDVQNHAYHDKYGRVYTSVIPCNIFGPHDNYNPEVSHVIPGMIYRMHQLVTEKTD 197
            |:||::|||:|||||.....:|||.||:.|..|:||.|||:|.|..||:||:|::.:....|
Zfish   163 NFGYAFAKRMIDVQNRTCFKQYGRRYTAGILTNVFGAHDNFNIEDGHVLPGLIHKTYLAKKE--- 224

  Fly   198 VPENDKVFTVFGSGMPLRQFVYSRDLAELMIWVLRNYESVEPIILSADEVQEVTIFEVAQAVAKA 262
                .|...|:|||.|||||:||.|||.|.:||||.|:.|:|||||..|..|::|.:.|.||..|
Zfish   225 ----GKPLQVWGSGKPLRQFIYSLDLARLFLWVLREYDEVDPIILSVGEEDELSIKDCADAVVDA 285

  Fly   263 FNFNGRLVCDTSKSDGQYKKTASNAKLRSFLPDYAFTDLETAINASVKWYIENYDQARK 321
            ..|||.::.||||:|||:||||||||||.:|||:.||....||..:..|::.|||.|||
Zfish   286 LGFNGDVIYDTSKADGQFKKTASNAKLRQYLPDFQFTPFREAIKETCDWFVANYDIARK 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gmer	NP_611734.1	GDP_FS_SDR_e	3..313	CDD:187550	183/309 (59%)
Gmer	NP_611734.1	Epimerase	4..234	CDD:279681	141/229 (62%)
gfus.3	NP_001070752.2	GDP_FS_SDR_e	33..335	CDD:187550	182/308 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580794
Domainoid	1	1.000	304	1.000	Domainoid score	I1350
eggNOG	1	0.900	-	-		E1_COG0451
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	398	1.000	Inparanoid score	I1897
OMA	1	1.010	-	-		QHG62684
OrthoDB	1	1.010	-	-		D419698at33208
OrthoFinder	1	1.000	-	-		FOG0003311
OrthoInspector	1	1.000	-	-		otm25254
orthoMCL	1	0.900	-	-		OOG6_102554
Panther	1	1.100	-	-	O	PTHR43238
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2209
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770