Protein Alignment Gmer and hsd3b2

DIOPT Version :10

• Sequence 1: NP_611734.1
• Gene: Gmer / 37638
• FlyBaseID: FBgn0267823
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_997962.1
• Gene: hsd3b2 / 373131
• ZFINID: ZDB-GENE-030828-2
• Length: 374
• Species: Danio rerio
• Alignment Length: 375
• Identity: 71/375 - (18%)
• Similarity: 127/375 - (33%)
• Gaps: 103/375 - (27%)

  Fly     5 LVTGGTGLVGKALEAVIKE-------------------QSPEDEQWFFAGS------KDADLTNL 44
            :|||..|.:|:.|..::.|                   |:.||.:.....|      :|.:|...
Zfish     9 VVTGACGFLGEKLVRLLLEEENLSEIRLLDRNIRSELIQTLEDGRGETKVSVIEGDIRDRELLRR 73

  Fly    45 AATQALFAREKPTHVIHLAAMV---GGLFHNMNNNLDFLRNNLLINDNVLQTAHEQGCVKVVSCL 106
            |...|       |.|.|.|:::   |.:.::..:.::.....||     |:|..:|.....:...
Zfish    74 ACKGA-------TLVFHTASLIDYNGAVEYSELHAVNVKATRLL-----LETCIQQSVSSFIYTS 126

  Fly   107 S---TCIFPDKTSYPIDETMVHNGPPHPSNY---GYSYAKR-----LIDVQNHAYHDKYGRVYTS 160
            |   .|  |:::..||...  |...|: |:|   .||..|:     .:........|. |.:.|.
Zfish   127 SIEVAC--PNRSGEPIING--HEDTPY-SSYPISNYSKTKQEAEQICLQANGELLRDG-GHLATC 185

  Fly   161 VI-PCNIFGPHDNY--NPEVSHVIPGMI-YRMHQLVTEKTDVPENDKVFTVFGSGMPLR------ 215
            .: |..|:||...:  |.....:..|.: :|:.|...:...|...:.......:|..||
Zfish   186 ALRPMFIYGPGCRFTLNKLRDAIRSGNVQHRLSQQSAKVNPVYVGNAALAHLQAGRALRDPEKRA 250

  Fly   216 ----QFVYSRDLAELMIWVLRNYESVEPIILSADEVQEVTIF---------EVAQAVAK------ 261
                .|.|..|....:.:....:..:.|:..|......:.||         |:.|||.:
Zfish   251 VVGGNFYYVSDDTPHISYCDLTHALMSPLGFSIQNKPILPIFLLYLLAFFMEILQAVLRPVLRFT 315

  Fly   262 -------------AFNFNGRLVCD----TSKSDGQYKKTASNAKLRSFLP 294
                         .|:|:.:..|.    :.:.|.:..:.::...|.|.||
Zfish   316 PPLNRQLVTMVNTPFSFSYQKACREFGYSPRYDWEEARRSTTDWLASVLP 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gmer	NP_611734.1	GDP_FS_SDR_e	3..313	CDD:187550	71/375 (19%)
hsd3b2	NP_997962.1	Rossmann-fold NAD(P)(+)-binding proteins	7..359	CDD:473865	67/367 (18%)