Protein Alignment Gmer and HSD3B2

DIOPT Version :10

• Sequence 1: NP_611734.1
• Gene: Gmer / 37638
• FlyBaseID: FBgn0267823
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_000189.1
• Gene: HSD3B2 / 3284
• HGNCID: 5218
• Length: 372
• Species: Homo sapiens
• Alignment Length: 204
• Identity: 50/204 - (24%)
• Similarity: 77/204 - (37%)
• Gaps: 58/204 - (28%)

  Fly     5 LVTGGTGLVG-------------KALEAVIKEQSPEDEQWFFAGSKDADLTNLAATQALF----- 51
            ||||..||:|             |.:.|:.|...||..:.|   ||..:.|.|...:...
Human     6 LVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEF---SKLQNRTKLTVLEGDILDEPF 67

  Fly    52 ---AREKPTHVIHLAAMVG--GLFHN---MNNNLDFLRNNLLINDNVLQTAHEQGCVKVVSCLST 108
               |.:..:.|||.|.::.  |:.|.   ||.|:.        ...:|..|..|..|.|....|:
Human    68 LKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVK--------GTQLLLEACVQASVPVFIYTSS 124

  Fly   109 CIFPDKTSYPIDETMVHNGP---------PHPSNYGYSYAKRLID---VQNHAYHDKYG-RVYTS 160
            .......||   :.::.||.         |.|    |.|:|:|.:   :..:.::.|.| .:||.
Human   125 IEVAGPNSY---KEIIQNGHEEEPLENTWPTP----YPYSKKLAEKAVLAANGWNLKNGDTLYTC 182

  Fly   161 VI-PCNIFG 168
            .: |..|:|
Human   183 ALRPTYIYG 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gmer	NP_611734.1	GDP_FS_SDR_e	3..313	CDD:187550	50/204 (25%)
HSD3B2	NP_000189.1	3b-HSD_HSDB1_like_SDR_e	4..356	CDD:187671	50/204 (25%)