Protein Alignment Gmer and HSD3B1

DIOPT Version :9

• Sequence 1: NP_611734.1
• Gene: Gmer / 37638
• FlyBaseID: FBgn0267823
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_000853.1
• Gene: HSD3B1 / 3283
• HGNCID: 5217
• Length: 373
• Species: Homo sapiens
• Alignment Length: 382
• Identity: 76/382 - (19%)
• Similarity: 122/382 - (31%)
• Gaps: 107/382 - (28%)

  Fly     5 LVTGGTGLVG-KALEAVIKEQ------------SPEDEQWFFAGSKDADLTNLAATQALF----- 51
            ||||..|.:| :.:..::||:            .||..:.|   ||..:.|.|...:...
Human     7 LVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEF---SKLQNKTKLTVLEGDILDEPF 68

  Fly    52 ---AREKPTHVIHLAAMVG--GLFHN---MNNNLDFLRNNLLINDNVLQTAHEQGCVKVVSCLST 108
               |.:..:.:||.|.::.  |:.|.   ||.|:.        ...:|..|..|..|.|....|:
Human    69 LKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVK--------GTQLLLEACVQASVPVFIYTSS 125

  Fly   109 CIFPDKTSYPIDETMVHNGP---------PHPSNYGYSYAKRLIDVQNHAYHDKYGRVYTSVI-P 163
            .......||   :.::.||.         |.|..:....|::.:...|.......|.:||..: |
Human   126 IEVAGPNSY---KEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTLYTCALRP 187

  Fly   164 CNIFGPHDNY------------------------NPEVSHVIPGMIYRMHQLVTEKTDVPENDKV 204
            ..|:|....:                        ||    |..|.:...|.|.......|:  |.
Human   188 MYIYGEGSRFLSASINEALNNNGILSSVGKFSTVNP----VYVGNVAWAHILALRALQDPK--KA 246

  Fly   205 FTVFGSGMPLRQFVYSRDLAELMIWVLRNYESVEPIILSADE--------------VQEVTIFEV 255
            .::.|      ||.|..|......:...||...:...|..|.              :.|:..|.:
Human   247 PSIRG------QFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMYWIGFLLEIVSFLL 305

  Fly   256 AQAVAKAFNFNGRLV-CDTSKSDGQYKKTASNAKLRSFLPDYAFTDLETAINASVKW 311
            .........||..:| ...|.....|||...:.   ::.|.|::   |.|...:|:|
Human   306 RPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDL---AYKPLYSW---EEAKQKTVEW 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gmer	NP_611734.1	GDP_FS_SDR_e	3..313	CDD:187550	76/382 (20%)
		Epimerase	4..234	CDD:279681	57/288 (20%)
HSD3B1	NP_000853.1	3b-HSD_HSDB1_like_SDR_e	5..357	CDD:187671	76/382 (20%)
		3Beta_HSD	7..287	CDD:279420	61/305 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0451
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900