DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gmer and Uxs1

DIOPT Version :9

Sequence 1:	NP_611734.1	Gene:	Gmer / 37638	FlyBaseID:	FBgn0267823	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	XP_038938945.1	Gene:	Uxs1 / 246232	RGDID:	628680	Length:	459	Species:	Rattus norvegicus

Alignment Length:	331	Identity:	75/331 - (22%)
Similarity:	125/331 - (37%)	Gaps:	48/331 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KKVLVTGGTGLVGKAL---------EAVIKE-----QSPEDEQWFFAGSKDADLTNLAATQALFA 52
            |::|:|||.|.||..|         |..:.:     :....|.|.  |.::.:|.|....:.|:.
  Rat   128 KRILITGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRKRNVEHWI--GHENFELINHDVVEPLYI 190

  Fly    53 REKPTHVIHLAAMVGGLFHNMNNNLDFLRNNLLINDNVLQTAHEQGCVKVVSCLSTCIFPDKTSY 117
              :...:.|||:..... :.|.|.:..|:.|.:...|:|..|...|...:::..|. ::.|...:
  Rat   191 --EVDQIYHLASPASPP-NYMYNPIKTLKTNTIGTLNMLGLAKRVGARLLLASTSE-VYGDPEVH 251

  Fly   118 PIDETMVHNGPPHPSNYGYSYAKRLIDVQNHAYHDKYG------RVYTSVIPCNIFGPHDNYNPE 176
            |..|....:..|......|...||:.:...:||..:.|      |::      |.|||..:.|.
  Rat   252 PQSEDYWGHVNPIGPRACYDEGKRVAETMCYAYMKQEGVEVRVARIF------NTFGPRMHMND- 309

  Fly   177 VSHVIPGMIYRMHQLVTEKTDVPENDKVFTVFGSGMPLRQFVYSRDLAELMIWVLRNYESVEPII 241
             ..|:...|.:..|           .:..||:|||...|.|.|..||...:: .|.|.....|:.
  Rat   310 -GRVVSNFILQALQ-----------GEPLTVYGSGSQTRAFQYVSDLVNGLV-ALMNSNVSSPVN 361

  Fly   242 LSADEVQEVTIFEVAQAVAKAFNFNGRLVCDTSKSDGQYKKTASNAKLRSFLPDYAFTDLETAIN 306
            |...|  |.||.|.||.:.........:...:...|...|:.....|.:..|.......||..:|
  Rat   362 LGNPE--EHTILEFAQLIKNLVGSGSEIQFLSEAQDDPQKRKPDIKKAKLMLGWEPVVPLEEGLN 424

  Fly   307 ASVKWY 312
            .::.::
  Rat   425 KAIHYF 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gmer	NP_611734.1	GDP_FS_SDR_e	3..313	CDD:187550	74/330 (22%)
Gmer	NP_611734.1	Epimerase	4..234	CDD:279681	57/249 (23%)
Uxs1	XP_038938945.1	UXS1_N	<64..117	CDD:403108
Uxs1	XP_038938945.1	UGD_SDR_e	128..431	CDD:187541	75/331 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0451
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810