Protein Alignment Gmer and hsd-1

DIOPT Version :10

• Sequence 1: NP_611734.1
• Gene: Gmer / 37638
• FlyBaseID: FBgn0267823
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_493402.1
• Gene: hsd-1 / 189371
• WormBaseID: WBGene00012394
• Length: 462
• Species: Caenorhabditis elegans
• Alignment Length: 392
• Identity: 78/392 - (19%)
• Similarity: 136/392 - (34%)
• Gaps: 148/392 - (37%)

  Fly     3 KVLVTGGTGLVGKALEAVIKEQSP-----------EDEQWFFAGSK-DADLT------------- 42
            |||:|||.|.:.:.|.|.::|.:.           |.|......:| |.::.
 Worm    46 KVLITGGAGHLAENLVAKLEEMTRDSIRPKIREMLEKEMPAVISTKVDKEVEKRLPMYIQIVLVD 110

  Fly    43 -----------NLAATQALF--------AREKPTHVIHLAA--MVGGLFHNMNNNLDFLRNNLLI 86
                       ::|..:..|        |.|:...|.||||  |.|....:....:|.   |.:.
 Worm   111 VLEPRGRVLKHHVAFVKCSFDDECTMKTALEQVDTVYHLAAVGMTGQYARDRKACMDI---NAVG 172

  Fly    87 NDNVLQTAHEQGCVKVVSCLST-CIFPDKTSYPIDETMVHNGPPHPSN-YGY-----SYAKRLID 144
            ..|:|..|...|..:.:...|. .:|..:..|...|.:     .:|.: |.|     ::|:|:
 Worm   173 TMNLLIWARNSGVQRFIYTSSVGVVFSGEPMYNATEEV-----GYPDDFYNYYCESKAHAERI-- 230

  Fly   145 VQNHAYHDKYGRVYTSVIPCN-IFGPHDNYNPE----------------------------VSHV 180
            ||..:.|    |:.|:|:..| |:||.:....|                            |::.
 Worm   231 VQKASGH----RMRTTVLRFNGIYGPGEKRVTERVVKFMLTGMWIATCKPNGVEAQTQLSSVANC 291

  Fly   181 IPGMIYRMHQLVTEKTDVPENDKVFTV--------------------FGSGM------PLRQFVY 219
            |.|::  ..:|....:|.| :.:::.:                    |.|.|      |:|.|.|
 Worm   292 IQGLV--KAELALRWSDTP-HGQIYNIMDKTPVGTFSFWTPLNIALGFSSSMITVPATPIRLFAY 353

  Fly   220 -SRDLAELMIWVLRNYESVEPIILSADEVQEVTIFEVAQAVAKAFNFNGRLVCDTSKSDGQYKKT 283
             |:.:|:.|        .::||:    .|.||.:.    .|...||.      :.::.|..|:.:
 Worm   354 LSQIIADRM--------RIDPIV----SVLEVDLL----LVNNTFNI------EKAERDLGYEPS 396

  Fly   284 AS 285
            .|
 Worm   397 VS 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gmer	NP_611734.1	GDP_FS_SDR_e	3..313	CDD:187550	78/392 (20%)
hsd-1	NP_493402.1	Rossmann-fold NAD(P)(+)-binding proteins	47..407	CDD:473865	77/391 (20%)