Protein Alignment Gmer and Hsd3b5

DIOPT Version :10

• Sequence 1: NP_611734.1
• Gene: Gmer / 37638
• FlyBaseID: FBgn0267823
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_032321.2
• Gene: Hsd3b5 / 15496
• MGIID: 104645
• Length: 373
• Species: Mus musculus
• Alignment Length: 342
• Identity: 60/342 - (17%)
• Similarity: 112/342 - (32%)
• Gaps: 107/342 - (31%)

  Fly     5 LVTGGTGLVGKALEAVI--KEQSPEDEQWF--FAGSKDADLTNL--------------------A 45
            ||||..|.:|:.:..::  :|:..|....|  |....:.:|:.|                    .
Mouse     7 LVTGAGGFLGQRIVRMLVQEEELQEIRALFRTFGRKHEEELSKLQTKAKVRVLKGDILDAQCLKR 71

  Fly    46 ATQALFAREKPTHVIHLAAMVGGLFHNMNNNLDFLRNNLLINDNVLQTAHEQGCVKVVSCLSTCI 110
            |.|.:.|      |||.||.:        :.|.......:::.|:..|.         ..|..|:
Mouse    72 ACQGMSA------VIHTAAAI--------DPLGAASRQTILDVNLKGTQ---------LLLDACV 113

  Fly   111 FPDKTSYPIDETMVHNGPPHPSNYGYSYAKRLIDVQNHAYHDKYGRVYTSVIPCNIFGPHDNYNP 175
            .....::....:::..||       .||.:.:::.....:.:       |..|          ||
Mouse   114 EASVPTFIYSSSVLVAGP-------NSYKEIILNAHEEEHRE-------STWP----------NP 154

  Fly   176 EVSHVIPGMIYRMHQLVTEKTDVPENDKVFTVFGS--GMPLR-QFVYSRDLAELMIWVLRNYESV 237
                      |...:.:.||..:..|.::....|:  ...|| .|:|..:...       ...:|
Mouse   155 ----------YPYSKRMAEKAVLATNGRLLKNGGTLHTCALRLPFIYGEECQV-------TSTTV 202

  Fly   238 EPIILSADEVQEVTIFEVAQAV-----AKAFNFNGRLVCDTSKS---DGQYKKTASNAKLRSFLP 294
            :..:.:...:::...|.:|..|     |.|.....|.:.|..||   .||:...:.|.      |
Mouse   203 KTALKNNSIIKKNATFSIANPVYVGNAAWAHILAARSLQDPKKSPSIQGQFYYISDNT------P 261

  Fly   295 DYAFTDLETAINASVKW 311
            ..::.||...:  |.:|
Mouse   262 HQSYDDLNYTL--SKEW 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gmer	NP_611734.1	GDP_FS_SDR_e	3..313	CDD:187550	60/342 (18%)
Hsd3b5	NP_032321.2	Rossmann-fold NAD(P)(+)-binding proteins	5..357	CDD:473865	60/342 (18%)