DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gmer and Mat2b

DIOPT Version :9

Sequence 1:NP_611734.1 Gene:Gmer / 37638 FlyBaseID:FBgn0267823 Length:321 Species:Drosophila melanogaster
Sequence 2:NP_598778.1 Gene:Mat2b / 108645 MGIID:1913667 Length:334 Species:Mus musculus


Alignment Length:318 Identity:68/318 - (21%)
Similarity:112/318 - (35%) Gaps:88/318 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 KKVLVTGGTGLVGKALEAVIKEQSPEDEQWFFAGS---------KDADLTNLAATQALFAREKPT 57
            ::||:||.|||:|:   ||.||.  :...|...|.         :..:|.:..|...|....:|.
Mouse    29 RRVLITGATGLLGR---AVYKEF--QQSNWHTVGCGFRRARPKFEQVNLLDSEAVHHLIHDFQPH 88

  Fly    58 HVIHLAAMVGGLFHNMNNNLDFLRN--------NLLINDNVLQTAHEQGCVKVVSCLSTCIFPDK 114
            .::|.||         ....|.:.:        |:..:.|:.:.|...|.. ::...|..:| |.
Mouse    89 VIVHCAA---------ERRPDVVESQPDAASQLNVGASGNLAKEAAAIGAF-LIYISSDYVF-DG 142

  Fly   115 TSYPIDETMVHNGPPHPSNYGYSYAKRLIDVQNHAYHDKYGRVYTSVIPCNIFGPHDNYNP---- 175
            |:.|..|..:    |.|.|.   |.|..:|.:.....:..|..... ||. ::|..:....    
Mouse   143 TNPPYTEEDI----PSPLNL---YGKTKLDGEKAVLENNLGAAVLR-IPV-LYGEVEKLEESAVT 198

  Fly   176 ------EVSHVIPGMIYRMHQLVTEKTDVPENDKVFTVFGSGMPLRQFVYSRDLAELMIWVLRNY 234
                  :.|:....|.:...:..|...||..                  ..|.|||..:      
Mouse   199 VMFDKVQFSNKSANMDHWQQRFPTHVKDVAS------------------VCRQLAEKRM------ 239

  Fly   235 ESVEPII-----LSADEVQEVTIFEVAQAVAKAFNFNG---RLVCDTSKSDGQYKKTA 284
              ::|.|     .|.:|  ::|.:|:|.|:|.|||...   |.:.|:.....|..|.|
Mouse   240 --LDPSIKGTFHWSGNE--QMTKYEMACAIADAFNLPSSHLRPITDSPVIGAQRPKNA 293

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GmerNP_611734.1 GDP_FS_SDR_e 3..313 CDD:187550 68/317 (21%)
Epimerase 4..234 CDD:279681 51/256 (20%)
Mat2bNP_598778.1 dTDP_HR_like_SDR_e 30..316 CDD:187564 68/317 (21%)
RmlD_sub_bind 31..322 CDD:282214 68/316 (22%)
Required for interaction with MAT2A. /evidence=ECO:0000250|UniProtKB:Q9NZL9 319..334
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0451
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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