Protein Alignment YME1L and RPT3

DIOPT Version :10

• Sequence 1: NP_001246473.1
• Gene: YME1L / 37636
• FlyBaseID: FBgn0034792
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_010682.3
• Gene: RPT3 / 852003
• SGDID: S000002802
• Length: 428
• Species: Saccharomyces cerevisiae
• Alignment Length: 443
• Identity: 140/443 - (31%)
• Similarity: 209/443 - (47%)
• Gaps: 93/443 - (20%)

  Fly   151 GLLRPLFSQQQLNQIRGFKTDRSIEAEQKRNPTMTSRLKNALANSPQRLDGDTPLQAEKLRR--- 212
            |::.|:  ::.:.:....|:..|:.|:  .|.|:.:  .:||:|    ::.|...:.:||.:
Yeast     5 GIVTPV--EKAVEEKPAVKSYASLLAQ--LNGTVNN--NSALSN----VNSDIYFKLKKLEKEYE 59

  Fly   213 LLAKSEEHGFNKAESLKIAFAEGYLAAANSEDSPKSGKTMKYLKTLQTI-VVIVVFL-------G 269
            ||...|::..::...||     ..|..|..|           :|.:|:: :||..||       |
Yeast    60 LLTLQEDYIKDEQRHLK-----RELKRAQEE-----------VKRIQSVPLVIGQFLEPIDQNTG 108

  Fly   270 IFLSFFTTSNGSVFR--------------SIQLGNQ----VEVDP-------------EEINVTF 303
            |..|  ||....|.|              |:.|...    |::.|             |:.:||:
Yeast   109 IVSS--TTGMSYVVRILSTLDRELLKPSMSVALHRHSNALVDILPPDSDSSISVMGENEKPDVTY 171

  Fly   304 EDVKGCDEAKQELKEVVEF-LKSPEKFSNLGGKLPKGVLLVGPPGTGKTLLARAVAGEAKVPFFH 367
            .||.|.|..|||::|.||. |...:.:..:|...|:||||.||||||||:|.:|||...|..|..
Yeast   172 ADVGGLDMQKQEIREAVELPLVQADLYEQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTKAAFIR 236

  Fly   368 AAGPEFDEVLVGQGARRVRDLFKAAKARAPCVIFIDEIDSVGAKRTNSVLHPYANQT-------- 424
            ..|.||....:|:|.|.|||:|:.|:..||.:|||||:||:..||.::       ||
Yeast   237 VNGSEFVHKYLGEGPRMVRDVFRLARENAPSIIFIDEVDSIATKRFDA-------QTGSDREVQR 294

  Fly   425 -INQLLSEMDGFHQNAGVIVLGATNRRDDLDQALLRPGRFDVEVMVSTPDFTGRKE---ILSLYL 485
             :.:||::||||.|:..|.|:.||||.|.||.|||||||.|.:  :..|....|:|   |.....
Yeast   295 ILIELLTQMDGFDQSTNVKVIMATNRADTLDPALLRPGRLDRK--IEFPSLRDRRERRLIFGTIA 357

  Fly   486 TKI-LHDEIDLDMLARGTSGFTGADLENMINQAALRAAIDGAETVSMKHLETA 537
            :|: |..|.|||.|.......:||.:..::.:|.|||.......:....||.|
Yeast   358 SKMSLAPEADLDSLIIRNDSLSGAVIAAIMQEAGLRAVRKNRYVILQSDLEEA 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YME1L	NP_001246473.1	HflB	258..737	CDD:440233	118/333 (35%)
RPT3	NP_010682.3	PTZ00454	46..428	CDD:240423	130/392 (33%)