DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment YME1L and ftsh9

DIOPT Version :9

Sequence 1:	NP_001246473.1	Gene:	YME1L / 37636	FlyBaseID:	FBgn0034792	Length:	740	Species:	Drosophila melanogaster
Sequence 2:	NP_568892.1	Gene:	ftsh9 / 836004	AraportID:	AT5G58870	Length:	806	Species:	Arabidopsis thaliana

Alignment Length:	834	Identity:	266/834 - (31%)
Similarity:	406/834 - (48%)	Gaps:	170/834 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 FST--TTHSVPYLYLGNFSR--------KPHYY--------------SVNRTKLHGSAGAARLSK 42
            |||  :|.|:.||:..:|.|        .|:.:              |:|:.:.:...|.:| .|
plant    17 FSTCCSTSSLLYLHASSFFRDRSFGFRQNPNRFVSNSSIQLPQSVPGSINQERFNLWQGFSR-KK 80

  Fly    43 STSTSSRSHDLVLDLRNLLSRSSASIQGMVERAARLNGILDRRLVDDVL----AKVTSMLPSMRD 103
            ||| |||:   :::.:....::|:|     |...:.|....|:...:.|    .|.....|.::
plant    81 STS-SSRT---IVNCQEGDQKASSS-----EGEGKTNKDKGRKQGKNELWWSKGKKWQWKPIIQ- 135

  Fly   104 VRVTLEESATQIGRVQLQNYQFEVSLTGAAGSVPTGANVKVIPTITPGLLRP--------LF--- 157
                    |.:||.:.||                .|..:.|:..:.||:..|        .|
plant   136 --------AQEIGVMLLQ----------------LGIVMFVVRLLRPGIPLPGSEPRTQTTFMSV 176

  Fly   158 -----------SQQQLNQIRGF------KTDRSIEAEQKRNPTMTSRLKNALANSPQRL------ 199
                       .:.|..::.||      |.|.:::..:    |.:|.:|  |:.|.:.:
plant   177 PYSDFLSKVNNDEVQKVEVDGFHVLFKLKDDGNLQESE----TSSSSIK--LSESSETMLRSVAP 235

  Fly   200 ------------DGDTPLQAEKLRRLLAKSEEHGFNKAESLKIAFAEGYLAAANSEDSPKSGKTM 252
                        |..||.:     ::|..:.|.|                    |.|....|...
plant   236 TKRVVYSTTRPRDIKTPYE-----KMLENNVEFG--------------------SPDKRSGGFFN 275

  Fly   253 KYLKTLQTIVVIVVFLGIFLSFFTTSNGSVFRSIQL----GNQVEVDPEEINVTFEDVKGCDEAK 313
            ..|..|..|.|:...|..|...|:.|.....|:.:.    |.:|..|.|  .:||.||.|.||||
plant   276 SGLIVLFYIAVLAGLLHRFPVNFSQSTTGQLRTRKSGGPGGGKVSGDGE--TITFADVAGVDEAK 338

  Fly   314 QELKEVVEFLKSPEKFSNLGGKLPKGVLLVGPPGTGKTLLARAVAGEAKVPFFHAAGPEFDEVLV 378
            :||:|:|||||:|:::..||.:.|:||||||.|||||||||:|||||:.|||...:..||.|:.|
plant   339 EELEEIVEFLKNPDRYVRLGARPPRGVLLVGLPGTGKTLLAKAVAGESDVPFISCSASEFVELYV 403

  Fly   379 GQGARRVRDLFKAAKARAPCVIFIDEIDSVGAKRTNS---VLHPYANQTINQLLSEMDGFHQNAG 440
            |.||.||||||..||..||.:|||||||:|...|...   |.:....||:||||:|||||..::.
plant   404 GMGASRVRDLFARAKKEAPSIIFIDEIDAVAKSRDGKFRMVSNDEREQTLNQLLTEMDGFDSSSA 468

  Fly   441 VIVLGATNRRDDLDQALLRPGRFDVEVMVSTPDFTGRKEILSLYLTK---ILHDEIDLDMLARGT 502
            |||||||||.|.||.||.||||||..|.|.:||..||:.||.::::|   .|.|:::|..:|..|
plant   469 VIVLGATNRADVLDPALRRPGRFDRVVTVESPDKVGRESILKVHVSKKELPLGDDVNLASIASMT 533

  Fly   503 SGFTGADLENMINQAALRAAIDGAETVSMKHLETARDKVLMGPERK-ARLPDEEANTITAYHEGG 566
            :|||||||.|::|:|||.|......||.......|.::.:.|.|:| |||...| ..:.|.||.|
plant   534 TGFTGADLANLVNEAALLAGRKSKMTVDKIDFIHAVERSIAGIEKKTARLKGSE-KAVVARHEAG 597

  Fly   567 HAI----VAFYTKESHPLHKVTIMPR-GPSLGHTAYIP--EKERYHVTKAQLLAMMDTMMGGRAA 624
            ||:    ||........:.|::|:|| |.:||.| |||  .::||.:...:|...:.|::|||||
plant   598 HAVVGTAVASLLSGQSRVEKLSILPRSGGALGFT-YIPPTHEDRYLLFIDELHGRLVTLLGGRAA 661

  Fly   625 EELVFGTDKITSGASSDLKQATSIATHMVRDWGMSDKVGLRTIEASKGLGTGDTLGP-------N 682
            ||:|: :.:|::||..|:::||.:|...|.::|:::|:|..::......|..|:.|.       :
plant   662 EEVVY-SGRISTGALDDIRRATDMAYKAVAEYGLNEKIGPVSVATLSAGGIDDSGGSPWGRDQGH 725

  Fly   683 TIEAVDAEIKRILSDSYERAKAILRKHTREHKALAEALLKYETLDADDIKAILN 736
            .::.|..|:..:|..:.:.|..::|.:....:.|...|...|.::.::::..||
plant   726 LVDLVQREVTNLLQSALDVALTVVRANPDVLEGLGAQLEDEEKVEGEELQKWLN 779

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
YME1L	NP_001246473.1	FtsH_fam	254..736	CDD:273520	205/506 (41%)
ftsh9	NP_568892.1	FtsH_fam	322..759	CDD:273520	191/441 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0465
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D217929at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820