Protein Alignment YME1L and VAR2

DIOPT Version :10

• Sequence 1: NP_001246473.1
• Gene: YME1L / 37636
• FlyBaseID: FBgn0034792
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_001323509.1
• Gene: VAR2 / 817646
• AraportID: AT2G30950
• Length: 699
• Species: Arabidopsis thaliana
• Alignment Length: 716
• Identity: 250/716 - (34%)
• Similarity: 384/716 - (53%)
• Gaps: 87/716 - (12%)

  Fly    61 LSRSSASIQGMVERAARLNGILDRRLVDDVLAKVTSMLPSMRD-----VRVTLEESATQIGR--- 117
            ::.|||.:.|   ....:|....:||......:.||....:|.     |:.:|:....|.||
plant     5 MAASSACLVG---NGLSVNTTTKQRLSKHFSGRQTSFSSVIRTSKVNVVKASLDGKKKQEGRRDF 66

  Fly   118 --VQLQNYQFEVSLTGAAGSVPTGANVKVIPTITPGLLRPLFSQ--QQLNQIRGFKTD----RSI 174
              :.|.|....:..:|.|.:...|.:..          |..:|:  :.|::.|..|.|    .:|
plant    67 LKILLGNAGVGLVASGKANADEQGVSSS----------RMSYSRFLEYLDKDRVNKVDLYENGTI 121

  Fly   175 EAEQKRNPTMTSRLKNALANSPQRLDGDTPLQAEKLRRLLAKSEEHGFNKAESLKIAFAEGYLAA 239
            ...:..:|.:.:|::......|       .|..|.|::|.||:.:                 .||
plant   122 AIVEAVSPELGNRVERVRVQLP-------GLSQELLQKLRAKNID-----------------FAA 162

  Fly   240 ANSEDSPKSGKTMKYLKTLQTIVVIVVFLGIFL-SFFTTSN---------GSVFRSIQLGN---Q 291
            .|:::...|        .|..::..:.|..:.: ..|..|.         |.....:|.|.   :
plant   163 HNAQEDQGS--------VLFNLIGNLAFPALLIGGLFLLSRRSGGGMGGPGGPGNPLQFGQSKAK 219

  Fly   292 VEVDPEEINVTFEDVKGCDEAKQELKEVVEFLKSPEKFSNLGGKLPKGVLLVGPPGTGKTLLARA 356
            .:::| ...|||:||.|.|||||:..|||||||.||:|:.:|.|:||||||:|||||||||||:|
plant   220 FQMEP-NTGVTFDDVAGVDEAKQDFMEVVEFLKKPERFTAVGAKIPKGVLLIGPPGTGKTLLAKA 283

  Fly   357 VAGEAKVPFFHAAGPEFDEVLVGQGARRVRDLFKAAKARAPCVIFIDEIDSVGAKRTNSV--LHP 419
            :||||.||||..:|.||.|:.||.||.|||||||.||..|||::|:||||:||.:|...:  .:.
plant   284 IAGEAGVPFFSISGSEFVEMFVGVGASRVRDLFKKAKENAPCIVFVDEIDAVGRQRGTGIGGGND 348

  Fly   420 YANQTINQLLSEMDGFHQNAGVIVLGATNRRDDLDQALLRPGRFDVEVMVSTPDFTGRKEILSLY 484
            ...||:||||:|||||..|.||||:.||||.|.||.|||||||||.:|.|..||..||.:||.::
plant   349 EREQTLNQLLTEMDGFEGNTGVIVVAATNRADILDSALLRPGRFDRQVSVDVPDVKGRTDILKVH 413

  Fly   485 L-TKILHDEIDLDMLARGTSGFTGADLENMINQAALRAAIDGAETVSMKHLETARDKVLMGPERK 548
            . .|...:::.|:::|..|.||:||||.|::|:||:.|......::|.|.::.:.|:::.|.|..
plant   414 AGNKKFDNDVSLEIIAMRTPGFSGADLANLLNEAAILAGRRARTSISSKEIDDSIDRIVAGMEGT 478

  Fly   549 ARLPDEEANTITAYHEGGHAIVAFYTKESHPLHKVTIMPRGPSLGHTAYIPEKERYHVTKAQLLA 613
            . :.|.::.::.||||.|||:....|.....:.|||::|||.:.|.|.:||..:...::|.||.|
plant   479 V-MTDGKSKSLVAYHEVGHAVCGTLTPGHDAVQKVTLIPRGQARGLTWFIPSDDPTLISKQQLFA 542

  Fly   614 MMDTMMGGRAAEELVFGTDKITSGASSDLKQATSIATHMVRDWGMSDKVGLRTIEASKG------ 672
            .:...:|||||||::||..::|:||..||:|.|.:|..||..:|||| :|..::..|..
plant   543 RIVGGLGGRAAEEIIFGDSEVTTGAVGDLQQITGLARQMVTTFGMSD-IGPWSLMDSSAQSDVIM 606

  Fly   673 -LGTGDTLGPNTIEAVDAEIKRILSDSYERAKAILRKHTREHKALAEALLKYETLDADDIKAILN 736
             :...:::.....|.:|:.:|::...:||.|.:.::.:......|.|.||:.||:..|:.:|||:
plant   607 RMMARNSMSEKLAEDIDSAVKKLSDSAYEIALSHIKNNREAMDKLVEVLLEKETIGGDEFRAILS 671

  Fly   737 E 737
            |
plant   672 E 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YME1L	NP_001246473.1	HflB	258..737	CDD:440233	209/501 (42%)
VAR2	NP_001323509.1	ftsH	89..680	CDD:214386	231/629 (37%)