Protein Alignment YME1L and yme1l1a

DIOPT Version :10

• Sequence 1: NP_001246473.1
• Gene: YME1L / 37636
• FlyBaseID: FBgn0034792
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: XP_005162918.2
• Gene: yme1l1a / 793098
• ZFINID: ZDB-GENE-091113-41
• Length: 729
• Species: Danio rerio
• Alignment Length: 790
• Identity: 352/790 - (44%)
• Similarity: 463/790 - (58%)
• Gaps: 124/790 - (15%)

  Fly     1 MFSTTTH-----SVPYLYLGNFSRKPHYYSVNRTKLHGSAGAARLSKSTSTS---SRSHDLV--- 54
            |||..|.     :||..:|.|..:          .|..||.:|..:...|..   |..||.:
Zfish     1 MFSLPTSFQSQGTVPLTHLINVVQ----------YLKSSANSAVTASVQSLQKDLSPEHDPLHYE 55

  Fly    55 --LDLRNLLSRSSASIQGMVE-RAARLNGILDRRLVDDVLAKVTSMLPSMRDVR-----VTLEES 111
              ::|:.|         |:.| |.:.:..:|:|            :|||.....     |....:
Zfish    56 PKVNLKEL---------GLSELRVSHVRDVLER------------LLPSTHPAEKSFASVAQNST 99

  Fly   112 ATQIGRVQ----LQN-YQFEVSLTGAAGSVPTGANVKVIPTITPGLLRPLFSQ-------QQLNQ 164
            |.:...:.    .|| |.|....:|..||          .....|...||.:.       |...|
Zfish   100 AWRTSHISAPSFFQNKYGFSHKHSGCFGS----------SVFRRGGSSPLQAACVDLHHLQLWVQ 154

  Fly   165 IRGFKTDRSIEAEQKRNPTMTSRLKNALANSPQRLDGDTP------LQAEK-----LRRLLAKS- 217
            .|||||            ...||...:.:..|...|..||      :..||     |.:||.::
Zfish   155 NRGFKT------------MSKSRHLRSSSEGPVEADNYTPVFMKGLIMKEKTDTGSLEQLLKQNN 207

  Fly   218 --EEHGFNKAESLKIAFAEGYLAAANSEDSPKSGKTMKYLKTLQTIVVIVVFLGIF---LSFFTT 277
              |.|    .::.|..|.||::.|     ...:.:|...:|..:.|:.:::..||:   .|.|.:
Zfish   208 LPESH----QDAFKTGFTEGFMKA-----QALTKRTQDSVKRTRLIIFVLLLAGIYGVSRSPFFS 263

  Fly   278 SNGSVFRSIQL----GNQVEVDPEEI-NVTFEDVKGCDEAKQELKEVVEFLKSPEKFSNLGGKLP 337
            ..||...:::.    |....|||.:: |:|||.|||.:|||.||::|||||::|:||:.||||||
Zfish   264 GKGSFSDTVRFRTTSGLDSSVDPVQMKNITFEHVKGVEEAKNELQDVVEFLRNPQKFTVLGGKLP 328

  Fly   338 KGVLLVGPPGTGKTLLARAVAGEAKVPFFHAAGPEFDEVLVGQGARRVRDLFKAAKARAPCVIFI 402
            ||:|||||||||||||||||||||.|||::|:|.||||:.||.||.|:|:|||.|||.|||||||
Zfish   329 KGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFKEAKASAPCVIFI 393

  Fly   403 DEIDSVGAKRTNSVLHPYANQTINQLLSEMDGFHQNAGVIVLGATNRRDDLDQALLRPGRFDVEV 467
            ||:||||.||..|.:|||:.|||||||:|||||..|.||||:||||..:.||.||:||||||::|
Zfish   394 DELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIVIGATNFAEALDNALVRPGRFDMQV 458

  Fly   468 MVSTPDFTGRKEILSLYLTKILHDE-IDLDMLARGTSGFTGADLENMINQAALRAAIDGAETVSM 531
            .|..||..||.|||..||.||..|. ||.:::||||.||:||:|||::|||||:||.||.:.|:|
Zfish   459 TVPIPDVKGRTEILEWYLKKIKVDSAIDAEIIARGTVGFSGAELENLVNQAALKAAADGKDLVTM 523

  Fly   532 KHLETARDKVLMGPERKARLPDEEANTITAYHEGGHAIVAFYTKESHPLHKVTIMPRGPSLGHTA 596
            |.||.|:||:||||||::...|:...|||||||.||||||:|||::.|::|.|||||||||||.:
Zfish   524 KELEFAKDKILMGPERRSVEIDKRNKTITAYHESGHAIVAYYTKDAMPINKATIMPRGPSLGHVS 588

  Fly   597 YIPEKERYHVTKAQLLAMMDTMMGGRAAEELVFGTDKITSGASSDLKQATSIATHMVRDWGMSDK 661
            .:||.:|:..|:|||||.||..||||.|||||||.|:||||||||...||.||..||..:|||||
Zfish   589 LLPENDRWSETRAQLLAQMDVSMGGRVAEELVFGNDQITSGASSDFDGATKIAQMMVTRFGMSDK 653

  Fly   662 VGLRTI-EASKGLGTGDTLGPNTIEAVDAEIKRILSDSYERAKAILRKHTREHKALAEALLKYET 725
            :|:.|. :.:|.       .|.|..||:.||:.:|..||||||.||:.:::|||.||:|||.|||
Zfish   654 LGVMTYSDLTKH-------SPETRAAVEQEIRVLLQSSYERAKKILKTYSKEHKLLADALLTYET 711

  Fly   726 LDADDIKAIL 735
            |:|.:|:.||
Zfish   712 LNAKEIQMIL 721

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YME1L	NP_001246473.1	HflB	258..737	CDD:440233	287/488 (59%)
yme1l1a	XP_005162918.2	None