DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment YME1L and Bcs1l

DIOPT Version :9

Sequence 1:	NP_001246473.1	Gene:	YME1L / 37636	FlyBaseID:	FBgn0034792	Length:	740	Species:	Drosophila melanogaster
Sequence 2:	NP_001292581.1	Gene:	Bcs1l / 66821	MGIID:	1914071	Length:	418	Species:	Mus musculus

Alignment Length:	165	Identity:	47/165 - (28%)
Similarity:	80/165 - (48%)	Gaps:	16/165 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   312 AKQELKEVVEFLKSPEKFSNLGGKLPKGVLLVGPPGTGKTLLARAVAGEAK--VPFFHAAGPEFD 374
            |.:.:|::.||:.:|:.:.:.|....:|.||.||||.||:....|:|||.:  :...........
Mouse   198 ADRIVKDIREFIDNPKWYIDRGIPYRRGYLLYGPPGCGKSSFITALAGELEHSICLLSLTDSSLS 262

  Fly   375 EVLVGQGARRVRDLFKAAKARAPCVIFIDEIDSVGAKRTNSVLHPYANQ-----TINQLLSEMDG 434
            :       .|:..|...|..::  ::.::::|:....|..:|.:|...|     |.:.||:.:||
Mouse   263 D-------DRLNHLLSVAPQQS--LVLLEDVDAAFLSRDLAVENPIKYQGLGRLTFSGLLNALDG 318

  Fly   435 FHQNAGVIVLGATNRRDDLDQALLRPGRFDVEVMV 469
            .......||...||..|.||.||:||||.|::..|
Mouse   319 VASTEARIVFMTTNYIDRLDPALIRPGRVDLKEYV 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
YME1L	NP_001246473.1	FtsH_fam	254..736	CDD:273520	47/165 (28%)
Bcs1l	NP_001292581.1	BCS1_N	24..191	CDD:214980
		AAA	223..354	CDD:214640	41/140 (29%)
		AAA	226..355	CDD:278434	40/137 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0465
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810