DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment YME1L and bcs1l

DIOPT Version :9

Sequence 1:	NP_001246473.1	Gene:	YME1L / 37636	FlyBaseID:	FBgn0034792	Length:	740	Species:	Drosophila melanogaster
Sequence 2:	NP_001016865.1	Gene:	bcs1l / 549619	XenbaseID:	XB-GENE-1015027	Length:	419	Species:	Xenopus tropicalis

Alignment Length:	216	Identity:	58/216 - (26%)
Similarity:	99/216 - (45%)	Gaps:	39/216 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   304 EDVKGCDEAKQELKEVVEFLKSPEKFSNLGGKLPKGVLLVGPPGTGKTLLARAVAGEAKVPFFHA 368
            :||||             |:.:|:.:|:.|....:|.||.||||.||:....|:|||.
Frog   203 QDVKG-------------FIDNPKWYSDRGIPYRRGYLLYGPPGCGKSSFITALAGEL------- 247

  Fly   369 AGPEFDEVL--VGQGA---RRVRDLFKAAKARAPCVIFIDEIDSVGAKRTNSVLHPYANQ----- 423
               |:...|  :..|:   .|:..|...|..::  :|.::::|:....|..:..:|.|.|
Frog   248 ---EYSICLMSLSDGSLSDDRLNHLLSVAPQQS--IILLEDVDAAFVSRDLTKENPTAYQGMGRL 307

  Fly   424 TINQLLSEMDGFHQNAGVIVLGATNRRDDLDQALLRPGRFDVEVMVSTPDFTGRKEILSLYLTKI 488
            |.:.||:.:||.......||...||..|.||.||:||||.||:..|.   :....::..::| :.
Frog   308 TFSGLLNALDGVASTEARIVFMTTNHIDRLDPALIRPGRVDVKQYVG---YCTHWQLSQMFL-RF 368

  Fly   489 LHDEIDLDMLARGTSGFTGAD 509
            ..|:..::..|..::..:.:|
Frog   369 YPDQTAVEAEAFASAALSSSD 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
YME1L	NP_001246473.1	FtsH_fam	254..736	CDD:273520	58/216 (27%)
bcs1l	NP_001016865.1	BCS1_N	24..191	CDD:214980
bcs1l	NP_001016865.1	AAA	226..355	CDD:365803	45/143 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910