Protein Alignment YME1L and yme1

DIOPT Version :10

• Sequence 1: NP_001246473.1
• Gene: YME1L / 37636
• FlyBaseID: FBgn0034792
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_588514.1
• Gene: yme1 / 2538746
• PomBaseID: SPCC965.04C
• Length: 709
• Species: Schizosaccharomyces pombe
• Alignment Length: 500
• Identity: 242/500 - (48%)
• Similarity: 339/500 - (67%)
• Gaps: 17/500 - (3%)

  Fly   244 DSPKSGKTMKYLKTLQTIVVIVVFLGIFLSFFTTSNGSVFRSIQLGNQVEVDPEE---INVTFED 305
            |.|:..|..:..|.:..:.|...|:.:.:|.|..::|  ..:| :.|..|.:|.|   |||.|.|
pombe   207 DEPRFTKFFRIFKFIAGLSVASYFVLLGMSIFAETSG--LNNI-MTNTTEQEPMEERAINVRFSD 268

  Fly   306 VKGCDEAKQELKEVVEFLKSPEKFSNLGGKLPKGVLLVGPPGTGKTLLARAVAGEAKVPFFHAAG 370
            |:|.||||:||:|:|:||:.|..|:.||||||:||||.||||||||:|||||||||.||||..:|
pombe   269 VQGVDEAKEELEEIVDFLRDPTHFTRLGGKLPRGVLLTGPPGTGKTMLARAVAGEANVPFFFMSG 333

  Fly   371 PEFDEVLVGQGARRVRDLFKAAKARAPCVIFIDEIDSVGAKRTNSVLHPYANQTINQLLSEMDGF 435
            .:|||:.||.||:|||:||.||:.:||.:|||||:|::|.|| |:....:..||:||||.::|||
pombe   334 SQFDEMYVGVGAKRVRELFAAARKQAPSIIFIDELDAIGQKR-NARDAAHMRQTLNQLLVDLDGF 397

  Fly   436 HQNAG----VIVLGATNRRDDLDQALLRPGRFDVEVMVSTPDFTGRKEILSLYLTKI-LHDEIDL 495
            .:|..    |:.:||||..:.||.||.||||||..:.|..||..||..||..:...: |..::||
pombe   398 SKNEDLAHPVVFIGATNFPESLDPALTRPGRFDRHIHVPLPDVRGRLAILLQHTRHVPLGKDVDL 462

  Fly   496 DMLARGTSGFTGADLENMINQAALRAAIDGAETVSMKHLETARDKVLMGPERKARLPDEEANTIT 560
            .::|||||||.||||.|:|||||:.|:.:.:..|||:.||.::|::|||.|||:.....|...:|
pombe   463 SIIARGTSGFAGADLANLINQAAVYASKNLSTAVSMRDLEWSKDRILMGAERKSAFITPENKLMT 527

  Fly   561 AYHEGGHAIVAFYTKESHPLHKVTIMPRGPSLGHTAYIPEKERYHVTKAQLLAMMDTMMGGRAAE 625
            ||||||||:||.:||.:...:|.||||||.|||.|..:|:.::...|:.:.|||:|..|||||||
pombe   528 AYHEGGHALVALFTKNAMRPYKATIMPRGSSLGMTISLPDMDKDSWTREEYLAMLDVTMGGRAAE 592

  Fly   626 ELVFGTDKITSGASSDLKQATSIATHMVRDWGMSDKVGLRTIEASKGLGTGDTLGPNTIEAVDAE 690
            ||::|.|||||||.:|:.:||.:|..||.::||||::|..::||..     |.|.|.|...|::|
pombe   593 ELLYGKDKITSGAHNDIDKATQVARRMVTEFGMSDRIGPVSLEAEM-----DNLSPATRALVESE 652

  Fly   691 IKRILSDSYERAKAILRKHTREHKALAEALLKYETLDADDIKAIL 735
            ||.:|..||||:.::|:.|.:|..|||.||:.||.|.|:::..::
pombe   653 IKSLLEASYERSLSLLKSHKKELDALATALVDYEFLTAEEMNRVV 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YME1L	NP_001246473.1	HflB	258..737	CDD:440233	238/485 (49%)
yme1	NP_588514.1	HflB	<257..699	CDD:440233	229/446 (51%)