Protein Alignment YME1L and Psmc5

DIOPT Version :10

• Sequence 1: NP_001246473.1
• Gene: YME1L / 37636
• FlyBaseID: FBgn0034792
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_032976.1
• Gene: Psmc5 / 19184
• MGIID: 105047
• Length: 406
• Species: Mus musculus
• Alignment Length: 268
• Identity: 106/268 - (39%)
• Similarity: 155/268 - (57%)
• Gaps: 12/268 - (4%)

  Fly   293 EVDP-------EEI-NVTFEDVKGCDEAKQELKEVVEF-LKSPEKFSNLGGKLPKGVLLVGPPGT 348
            :|||       |:: :.|:|.:.|.|:..:|:|||:|. :|.||.|..||...||||||.|||||
Mouse   130 KVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGT 194

  Fly   349 GKTLLARAVAGEAKVPFFHAAGPEFDEVLVGQGARRVRDLFKAAKARAPCVIFIDEIDSVGAKRT 413
            ||||||||||......|...:|.|..:..:|:|||.||:||..|:..||.:||:|||||:|:.|.
Mouse   195 GKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRL 259

  Fly   414 --NSVLHPYANQTINQLLSEMDGFHQNAGVIVLGATNRRDDLDQALLRPGRFDVEVMVSTPDFTG 476
              .|.......:|:.:||:::|||.....:.|:.||||.|.||.|||||||.|.::....|:...
Mouse   260 EGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEA 324

  Fly   477 RKEILSLYLTKI-LHDEIDLDMLARGTSGFTGADLENMINQAALRAAIDGAETVSMKHLETARDK 540
            |.:||.::..|: |...|:|..:|....|.:||:::.:..:|.:.|..:....|:.:..|.|..|
Mouse   325 RLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVAK 389

  Fly   541 VLMGPERK 548
            |:.....|
Mouse   390 VMQKDSEK 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YME1L	NP_001246473.1	HflB	258..737	CDD:440233	106/268 (40%)
Psmc5	NP_032976.1	PRK03992	24..400	CDD:179699	106/268 (40%)
		May mediate interaction with PRPF9. /evidence=ECO:0000269|PubMed:17349974	186..406		84/212 (40%)