Protein Alignment YME1L and spg-7

DIOPT Version :10

• Sequence 1: NP_001246473.1
• Gene: YME1L / 37636
• FlyBaseID: FBgn0034792
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_491165.2
• Gene: spg-7 / 171915
• WormBaseID: WBGene00004978
• Length: 782
• Species: Caenorhabditis elegans
• Alignment Length: 462
• Identity: 200/462 - (43%)
• Similarity: 283/462 - (61%)
• Gaps: 14/462 - (3%)

  Fly   280 GSVFRSIQLGNQVEVDPEEINVTFEDVKGCDEAKQELKEVVEFLKSPEKFSNLGGKLPKGVLLVG 344
            |.:|..........::.|:|.|.|.||.||:|||.|:.|.|.|||:|:::.:||.|:|||.:|.|
 Worm   269 GGMFGGFGQSTARVINREDIKVKFADVAGCEEAKIEIMEFVNFLKNPQQYKDLGAKIPKGAILTG 333

  Fly   345 PPGTGKTLLARAVAGEAKVPFFHAAGPEFDEVLVGQGARRVRDLFKAAKARAPCVIFIDEIDSVG 409
            ||||||||||:|.||||.|||...:|.||.|:.||.|..||||:|..|:..:||::||||||:||
 Worm   334 PPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDMFSMARKNSPCILFIDEIDAVG 398

  Fly   410 AKRTNS---VLHPYANQTINQLLSEMDGF-HQNAGVIVLGATNRRDDLDQALLRPGRFDVEVMVS 470
            .||...   ..|.....|:||||.||||| ...:.|||:.||||.|.||.|||||||||.::.|.
 Worm   399 RKRGGKGGMGGHSEQENTLNQLLVEMDGFTTDESSVIVIAATNRVDILDSALLRPGRFDRQIYVP 463

  Fly   471 TPDFTGRKEILSLYLTKILHDEIDLDMLAR----GTSGFTGADLENMINQAALRAAIDGAETVSM 531
            .||..||..|..::|.. |...:|..:|:|    .|.||:|||:.|:.|:|||.||.|....:|.
 Worm   464 VPDIKGRASIFRVHLGP-LRTSLDKTVLSRKLAAHTPGFSGADISNVCNEAALIAARDANHEISN 527

  Fly   532 KHLETARDKVLMGPERKARLPDEEANTITAYHEGGHAIVAFYTKESHPLHKVTIMPRGPSLGHTA 596
            ||.|.|.::|:.|.|:|.::..:|.....||||.||||..::.:.:.||.||:|:|||..||:..
 Worm   528 KHFEQAIERVVAGMEKKTQVLQKEEKKTVAYHEAGHAIAGWFLQHADPLLKVSIIPRGKGLGYAQ 592

  Fly   597 YIPEKERYHVTKAQLLAMMDTMMGGRAAEELVFGTDKITSGASSDLKQATSIATHMVRDWGMSDK 661
            |:| ||:|..:|.|||..|...:|||.|||:.||  :||:||..||::.|.:|...|..:|||:|
 Worm   593 YLP-KEQYLYSKDQLLDRMCMTLGGRVAEEIFFG--RITTGAQDDLQKVTQMAYSQVVKFGMSEK 654

  Fly   662 VGLRTIE--ASKGLGTGDTLGPNTIEAVDAEIKRILSDSYERAKAILRKHTREHKALAEALLKYE 724
            ||..:.|  |...:.........|.:.:|.|::.::.::..|.:.:|.:...:.:.:|..||:.|
 Worm   655 VGPLSFETPAPGEMAFDKPYSEATAQLIDQEVRDLVMNALRRTRDLLLEKRSDIERVALRLLEKE 719

  Fly   725 TLDADDI 731
            .|:.:|:
 Worm   720 ILNREDM 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YME1L	NP_001246473.1	HflB	258..737	CDD:440233	200/462 (43%)
spg-7	NP_491165.2	HflB	126..732	CDD:440233	200/462 (43%)