Protein Alignment YME1L and YME1L

DIOPT Version :10

• Sequence 1: NP_001246473.1
• Gene: YME1L / 37636
• FlyBaseID: FBgn0034792
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: XP_061509678.1
• Gene: YME1L / 1279395
• VectorBaseID: AGAMI1_003770
• Length: 764
• Species: Anopheles gambiae
• Alignment Length: 776
• Identity: 491/776 - (63%)
• Similarity: 568/776 - (73%)
• Gaps: 63/776 - (8%)

  Fly     1 MFSTTTHSVPYLYLGNFSR-KPHYYSV-----NRTKLHGSAGAARLSKSTSTSSRSHDLVLDLR- 58
            ||:..||....|:  :.|: .|.:.|:     :|...|......:..:...:.....|.|..|:
Mosquito     1 MFTVNTHQHQILF--HLSQITPRHSSIAFKKHHRHHQHHQQQQPQQGREAVSQLAQQDFVPRLKQ 63

  Fly    59 NLLSRSSASIQGMVERAARLNGILDRRLVDDVLAKVTSMLPSMRDVRVTLEESATQIGRVQLQNY 123
            :|::..:.:.:..||.:.              .....:.:||....|:.|..   ::.|..|:::
Mosquito    64 SLVTFYTDAFRSSVEPSP--------------AGAAPAQVPSEELYRLKLPR---RLERNLLKHF 111

  Fly   124 QFEVSLTGA-AGSVPTGANVKVIPTITPG------------------LLRPLFSQQ---QLNQIR 166
            . :|.|.|: ..|.|...|  |.|.:..|                  ::|.|.:|.   ...|.|
Mosquito   112 S-QVELLGSIKESTPWSLN--VTPKVKHGKCDAIAETVSFSGESVQKIVRSLLAQPTSWNTVQQR 173

  Fly   167 GFKTDRSIEAEQKRNPTMTSRLKNALAN---------SPQRLDGDT---PLQAEKLRRLLAKSEE 219
            ||||.|||.||.||||.:.:|:|:||.|         .|......|   ....|.|.:|||....
Mosquito   174 GFKTVRSISAELKRNPALYTRMKDALGNPAPPISHKYDPVAYSAQTIAPSAHGEPLNKLLADDPM 238

  Fly   220 HGFNKAESLKIAFAEGYLAAANSEDSPKSGKTMKYLKTLQTIVVIVVFLGIFLSFFTTSNGSVFR 284
            ....:.:.||||||||||.|:|.:...:|||.|||||..|.:::||||:|||:|.|.:.|||||.
Mosquito   239 LSDEQRQRLKIAFAEGYLTASNPDQQNRSGKAMKYLKFFQQLLIIVVFIGIFISMFASPNGSVFS 303

  Fly   285 SIQLGNQVEVDPEEINVTFEDVKGCDEAKQELKEVVEFLKSPEKFSNLGGKLPKGVLLVGPPGTG 349
            .||:|||||||||:|.||||||||||||||||||||||||:|.||||||||||||||||||||||
Mosquito   304 RIQIGNQVEVDPEDITVTFEDVKGCDEAKQELKEVVEFLKNPGKFSNLGGKLPKGVLLVGPPGTG 368

  Fly   350 KTLLARAVAGEAKVPFFHAAGPEFDEVLVGQGARRVRDLFKAAKARAPCVIFIDEIDSVGAKRTN 414
            ||||||||||||.|||||||||||||||||||||||||||||||.||||||||||||||||||||
Mosquito   369 KTLLARAVAGEAGVPFFHAAGPEFDEVLVGQGARRVRDLFKAAKERAPCVIFIDEIDSVGAKRTN 433

  Fly   415 SVLHPYANQTINQLLSEMDGFHQNAGVIVLGATNRRDDLDQALLRPGRFDVEVMVSTPDFTGRKE 479
            |||||||||||||||||||||.||.||||||||||||||||||||||||||||:|.|||||||||
Mosquito   434 SVLHPYANQTINQLLSEMDGFQQNEGVIVLGATNRRDDLDQALLRPGRFDVEVVVPTPDFTGRKE 498

  Fly   480 ILSLYLTKILHDEIDLDMLARGTSGFTGADLENMINQAALRAAIDGAETVSMKHLETARDKVLMG 544
            ||:.||.|||..||::|.|||||:||||||:|||:|||||||||||||||||||||.||||||||
Mosquito   499 ILTYYLGKILSREINIDQLARGTTGFTGADIENMVNQAALRAAIDGAETVSMKHLENARDKVLMG 563

  Fly   545 PERKARLPDEEANTITAYHEGGHAIVAFYTKESHPLHKVTIMPRGPSLGHTAYIPEKERYHVTKA 609
            ||||:||||||||.|||||||||||||:||||||||||||||||||||||||||||||||||||.
Mosquito   564 PERKSRLPDEEANKITAYHEGGHAIVAYYTKESHPLHKVTIMPRGPSLGHTAYIPEKERYHVTKQ 628

  Fly   610 QLLAMMDTMMGGRAAEELVFGTDKITSGASSDLKQATSIATHMVRDWGMSDKVGLRTIEASKGLG 674
            ||||||||||||||||||:||.||||||||||||||||||.|||::||||::|||||||..||.|
Mosquito   629 QLLAMMDTMMGGRAAEELIFGADKITSGASSDLKQATSIAAHMVKEWGMSERVGLRTIEGPKGFG 693

  Fly   675 TGDTLGPNTIEAVDAEIKRILSDSYERAKAILRKHTREHKALAEALLKYETLDADDIKAIL 735
            ..:.|.|:|||:||.|||::|::|||||||||::|.:|||||||||||||||||:|||||:
Mosquito   694 QNEVLSPSTIESVDNEIKKLLNESYERAKAILKQHAKEHKALAEALLKYETLDAEDIKAIM 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YME1L	NP_001246473.1	HflB	258..737	CDD:440233	410/478 (86%)
YME1L	XP_061509678.1	None