Protein Alignment YME1L and Bcs1

DIOPT Version :10

• Sequence 1: NP_001246473.1
• Gene: YME1L / 37636
• FlyBaseID: FBgn0034792
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: XP_313188.3
• Gene: Bcs1 / 1274111
• VectorBaseID: AGAMI1_001322
• Length: 424
• Species: Anopheles gambiae
• Alignment Length: 535
• Identity: 124/535 - (23%)
• Similarity: 183/535 - (34%)
• Gaps: 172/535 - (32%)

  Fly    13 YLGNFSRKPHYYSVNRTKLHGSAGAARLSKSTSTSSRSHDLVLDLRNLLSRSSASIQGMVERAAR 77
            |:|..|..| |:..........||||.|.|                        .:||.:
Mosquito     6 YIGALSENP-YFGAGFGLFGVGAGAAMLRK------------------------GMQGAM----- 40

  Fly    78 LNGILDRRLVDDVLAKVTSMLPSMRDVRVTLEESATQIGRVQLQNYQFEVSLTGA-AGSVPTGAN 141
               ||.||..     .:|..:|........|.:..||.|..|.|:...|.|.... .|.:.|  .
Mosquito    41 ---ILFRRHY-----MITLEVPCRDKSYQWLLQWITQKGARQTQHLSVETSFEQRDTGHIKT--R 95

  Fly   142 VKVIPTITPGLLRPLFSQQQLNQIRG--FKTDRSIEAEQKRNPTMTSRLKNALANSPQRLDGDTP 204
            ...||::...::|          ..|  .|.||:.|..     |:.             |....|
Mosquito    96 YDFIPSVGTHIMR----------YGGTWIKVDRAREQH-----TLD-------------LHMGVP 132

  Fly   205 LQAEKLRRLLAKSEEHGFNKAESLKIAFAEGYLAAANSEDSPKSGKTMKYLKTLQTIVVIVVFLG 269
            .:..:|...       |.:|....||......||..|:|     |||:.|
Mosquito   133 WETVQLTAF-------GRDKNLYFKILEEARQLALKNTE-----GKTIMY--------------- 170

  Fly   270 IFLSFFTTSNGSVFRSI-------QLGNQVEVDPEEINVTFEDVKGCDEAKQE--LKEVVEFLKS 325
                   |:.||.:|..       .:|:.|                .||...|  |::..||:|:
Mosquito   171 -------TAMGSEWRPFGHPRKRRPIGSVV----------------LDEGVSERILRDCREFIKN 212

  Fly   326 PEKFSNLGGKLPKGVLLVGPPGTGKTLLARAVAGEAKVPFFHAAGPEFDEVLVGQGAR-----RV 385
            |:.:|:.|....:|.||.||||.||:....|:|||.          ||...|:....|     |:
Mosquito   213 PQWYSDRGIPYRRGYLLHGPPGCGKSSFITALAGEI----------EFGICLLNLSERGLTDDRL 267

  Fly   386 RDLFKAAKARAPCVIFIDEIDSVGAKRTNSVLHPYANQTINQ-----LLSEMDGFHQNAGVIVLG 445
            ..|...|..::  :|.:::||:....|.:::....|.:.:|:     ||:.:||.......||..
Mosquito   268 NHLMNVAPQQS--IILLEDIDAAFVSRQDTLQQKAAYEGLNRVTFSGLLNCLDGVASTEARIVFM 330

  Fly   446 ATNRRDDLDQALLRPGRFDVEVMVSTPDFTGRKEILSLYLTKILHDEIDLDMLARGTSGFTGADL 510
            .||..:.||.||:||||.||:..|.   ...|.::..::                 ...:||.|.
Mosquito   331 TTNYLERLDPALIRPGRVDVKEYVG---HCSRHQLEQMF-----------------RRFYTGTDA 375

  Fly   511 ENMINQAALRAAIDG 525
            |......|.|.|.||
Mosquito   376 EANARIFAERVAADG 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YME1L	NP_001246473.1	HflB	258..737	CDD:440233	71/287 (25%)
Bcs1	XP_313188.3	BCS1_N	23..192	CDD:214980	53/269 (20%)
		RecA-like_BCS1	202..354	CDD:410918	51/163 (31%)