Protein Alignment YME1L and spg7

DIOPT Version :9

• Sequence 1: NP_001246473.1
• Gene: YME1L / 37636
• FlyBaseID: FBgn0034792
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: XP_002933705.2
• Gene: spg7 / 100485977
• XenbaseID: XB-GENE-6034036
• Length: 768
• Species: Xenopus tropicalis
• Alignment Length: 779
• Identity: 246/779 - (31%)
• Similarity: 381/779 - (48%)
• Gaps: 149/779 - (19%)

  Fly    33 GSAGAAR-LSKSTSTSSRSHDLVLDLRNLLSRS-SASIQGMVERAARLNGILDRRLVDD------ 89
            ||||..| :.::..:.||.      |:|||.|: :....||.|.      ::.|.|:.|
 Frog    14 GSAGCWRKVPRAECSESRI------LQNLLCRNLTPGSHGMREY------LIKRHLIQDPLRIWR 66

  Fly    90 VLAKVTSMLPSMRDVRVTLEESA------------------TQIGRVQLQNYQFEV--------S 128
            :|..:.....|.|..:....|.:                  .|:.|.:|:.. |.:        |
 Frog    67 ILGGINYFSTSGRGNKENQNEGSKGKTPHEDEEEKKRREREDQMYRERLRTL-FIIAVIMSLLNS 130

  Fly   129 LTGAAGSVPTG------------ANVKVIPT-------ITPGLL---RP---LFSQQQLNQIRGF 168
            |:.:.|::...            ..|:|:|.       :.||.:   ||   |..:.|:..|..|
 Frog   131 LSSSGGNISWNDFVNEMLAKGEVMRVQVVPESDIVEIYLYPGAVVFGRPRLALMYRMQVANIDKF 195

  Fly   169 KTDRSIEAEQKRNPTMTSRLKNALANSPQRLDGDTPLQAEKLRRLLAKSEEHGFNKAESLKIAFA 233
            :                                      ||||   |..||...|..:.:.:::.
 Frog   196 E--------------------------------------EKLR---AAEEELKINVKDRIPVSYK 219

  Fly   234 E-GYLAAANSEDSPKSGKTMKYLKTLQTIVVIVVFLGIFLSFFTTSNG--SVFRSIQLGNQVEVD 295
            . |:...|            .|...:..:.|.:::....|:......|  |.|..:::.....||
 Frog   220 RTGFFGNA------------LYALGMAAVGVAILWYIFRLAGMAGREGAFSAFNQLKMARFTIVD 272

  Fly   296 PEE-INVTFEDVKGCDEAKQELKEVVEFLKSPEKFSNLGGKLPKGVLLVGPPGTGKTLLARAVAG 359
            .:. ..::|:||.|..|||.|:||.|::||||:::..||.|:|||.||:||||.||||||:|||.
 Frog   273 GKSGKGISFKDVAGMHEAKLEVKEFVDYLKSPDRYLQLGAKVPKGALLLGPPGCGKTLLAKAVAT 337

  Fly   360 EAKVPFFHAAGPEFDEVLVGQGARRVRDLFKAAKARAPCVIFIDEIDSVGAKRTNSVLHPYAN-- 422
            ||:|||...||.||.||:.|.||.|||.|||.|:.||||:::|||||:||.||:.: :..::|
 Frog   338 EAQVPFLAMAGSEFVEVIGGLGAARVRSLFKEARTRAPCIVYIDEIDAVGKKRSTN-MSSFSNTE 401

  Fly   423 --QTINQLLSEMDGFHQNAGVIVLGATNRRDDLDQALLRPGRFDVEVMVSTPDFTGRKEIL---- 481
              ||:||||.||||......||||.:|||.|.||.||:||||.|..:.:..|....|:||.
 Frog   402 EEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDNALMRPGRLDRHIFIDLPTLQERREIFEQHL 466

  Fly   482 -SLYLTKILHDEIDLDMLARGTSGFTGADLENMINQAALRAAIDGAETVSMKHLETARDKVLMGP 545
             ||.||:  ........||..|.||:|||:.|:.|:|||.||.:|.:::...:.|.|.::|:.|.
 Frog   467 KSLKLTQ--PGSFYSQRLAELTPGFSGADIANICNEAALHAAREGYQSIDTFNFEYAVERVIAGT 529

  Fly   546 ERKARLPDEEANTITAYHEGGHAIVAFYTKESHPLHKVTIMPR-GPSLGHTAYIPEKERYHVTKA 609
            .:|:::..:|...:.|:||.|||:|.:..:.:..:.||:|.|| ..:||....:| :|:|..||.
 Frog   530 AKKSKIMSKEERRVVAFHESGHALVGWLLEHTEAVMKVSIAPRTNAALGFAQILP-REQYLYTKE 593

  Fly   610 QLLAMMDTMMGGRAAEELVFGTDKITSGASSDLKQATSIATHMVRDWGMSDKVGLRTI---EASK 671
            |||..|...:|||.:|.:.|  :|:|:||..||::.|.||..||:.:||...:|..:.   |::.
 Frog   594 QLLERMCMALGGRVSEAITF--NKVTTGAQDDLRKVTRIAYAMVKQYGMVPSIGQVSFPDSESTP 656

  Fly   672 GLGTGDTLGPNTIEAVDAEIKRILSDSYERAKAILRKHTREHKALAEALLKYETLDADDIKAIL 735
            |:|. ........|.:|.|.:.::|.:|.|.:.:|..:..:...|..|||:.|.::.|||:.::
 Frog   657 GIGR-RPFSQGLQEMMDREAQLLVSTAYRRTEKLLLDNRDKLILLTNALLEREVINYDDIEHLI 719

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YME1L	NP_001246473.1	FtsH_fam	254..736	CDD:273520	196/498 (39%)
spg7	XP_002933705.2	FtsH_ext	118..215	CDD:377663	23/138 (17%)
		FtsH_fam	239..720	CDD:273520	194/488 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D217929at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920