Protein Alignment PIP5K59B and MSS4

DIOPT Version :9

• Sequence 1: NP_001369113.1
• Gene: PIP5K59B / 37633
• FlyBaseID: FBgn0034789
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: NP_010494.1
• Gene: MSS4 / 851789
• SGDID: S000002616
• Length: 779
• Species: Saccharomyces cerevisiae
• Alignment Length: 482
• Identity: 148/482 - (30%)
• Similarity: 236/482 - (48%)
• Gaps: 69/482 - (14%)

  Fly     9 INTIDMDSSSASQAKLAEPSNASTDHVGNSSPDLGNRPNRASSK---ADKERKIGHRRVGEGGEI 70
            :|.....:::|:..|.:|.:.|....:..|.  |..|..:...|   .|.:|.:...:|.| |.:
Yeast   323 VNNNTTTTTAATGLKRSESATAEIKKMRQSL--LHKREMKRKRKTFLVDDDRVLIGNKVSE-GHV 384

  Fly    71 TYKKIQTSQIMGSIQLGIQHTVGSLASKPKRDLLMMDFWEIESITFPPEGSSLTPAHHYSEFRYK 135
            .:  |....::..|::.:....|.:  ||   |...||...:.:.|...|:.|||:..|: |::|
Yeast   385 NF--IIAYNMLTGIRVAVSRCSGIM--KP---LTPADFRFTKKLAFDYHGNELTPSSQYA-FKFK 441

  Fly   136 IYAPIAFRYFRDLFGIQPDDFMMSMCTSP--LRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEF 198
            .|.|..||..|.|||:.|.|:::|: ||.  |.||::||.|||.||.:.|.::||||:.|.|...
Yeast   442 DYCPEVFRELRALFGLDPADYLVSL-TSKYILSELNSPGKSGSFFYYSRDYKYIIKTIHHSEHIH 505

  Fly   199 LQKLLPGYYMNLNQNPRTLLPKFFGLYCLQTS-------NAKNIRLVVMNNLLPSSVKMHLKYDL 256
            |:|.:..||.::..||.||:.:|:||:.::..       ..:.|..:|||||.|..:.:|:.|||
Yeast   506 LRKHIQEYYNHVRDNPNTLICQFYGLHRVKMPISFQNKIKHRKIYFLVMNNLFPPHLDIHITYDL 570

  Fly   257 KGSTFKRKAN-KAERAKKS----PTYKDLDFMEQHPNGIF--LEAETYAALIKTIQRDCTVLESF 314
            ||||:.|..| ..||..|.    |..|||:::|:.....|  |:.:|:...:|   :|..:|...
Yeast   571 KGSTWGRFTNLDKERLAKDRSYRPVMKDLNWLEEGQKIKFGPLKKKTFLTQLK---KDVELLAKL 632

  Fly   315 KIMDYSLLLGVHNLDVALKEKQSEQRKPLRAPLAEDSDVDADDPLDGDAATGISRNKSVNRQRLV 379
            ..||||||:|:|:::   |.|:.:.:      ||:.:.::......|...||.
Yeast   633 NTMDYSLLIGIHDIN---KAKEDDLQ------LADTASIEEQPQTQGPIRTGT------------ 676

  Fly   380 AHSTAMESIQAESEPIDDEEDVPPGGIPARSE--KGERLLLYIGIIDILQSYRLKKKLEHTFKSI 442
              .|.:.....|.|          |||.|..:  ....|:.|:||||.|.:|.:.||||..::|:
Yeast   677 --GTVVRHFFREFE----------GGIRASDQFNNDVDLIYYVGIIDFLTNYSVMKKLETFWRSL 729

  Fly   443 IHDGETVSVCRPSFYAQRFQNFMAKTV 469
            .||.:.||...|..||.||..|:..:|
Yeast   730 RHDTKLVSAIPPRDYANRFYEFIEDSV 756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP5K59B	NP_001369113.1	PIPKc_PIP5KI	78..473	CDD:340438	133/410 (32%)
MSS4	NP_010494.1	MSS4	4..772	CDD:227578	148/482 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	154	1.000	Domainoid score	I904
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	192	1.000	Inparanoid score	I899
Isobase	1	0.950	-	0	Normalized mean entropy	S1569
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46604
orthoMCL	1	0.900	-	-		OOG6_100438
Panther	1	1.100	-	-	O	PTHR23086
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2198
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.800