DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PIP5K59B and AT1G60890

DIOPT Version :9

Sequence 1:	NP_001369113.1	Gene:	PIP5K59B / 37633	FlyBaseID:	FBgn0034789	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_001185275.1	Gene:	AT1G60890 / 842381	AraportID:	AT1G60890	Length:	781	Species:	Arabidopsis thaliana

Alignment Length:	555	Identity:	174/555 - (31%)
Similarity:	263/555 - (47%)	Gaps:	110/555 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TINTIDMDSSSASQAKLAEPSNAS----------TDHVGNSSPDLGNRPNRASSKADKERKIGHR 62
            |||..|:.:|.|....|:|.:..|          .|:...|.|......:..|||:.:....|..
plant   236 TINIDDLRTSKAVSRSLSELTTTSGLTRTSERYPDDYWSTSDPPRDFMHHGPSSKSARSVDSGQS 300

  Fly    63 RVGEGGEITYKK------IQTSQIMGSI------------------------------------Q 85
            .:.:...|.:::      :...:||.||                                    |
plant   301 EIRDKNPIVFEREYMQGVLIKERIMSSIDMSHRARPLNLTKEVTVSACVSFLGGKWNHYLMLNLQ 365

  Fly    86 LGIQHTVGSLASKPKRDLLMMDFWEIESIT--FPPEGSSLTPAHHYSEFRYKIYAPIAFRYFRDL 148
            |||::|||.:...|.|::...||.|...|.  ||..||..||.|...:|.:|.|.|:.||..|::
plant   366 LGIRYTVGKITPVPPREVRASDFSERARIMMFFPRNGSQYTPPHKSIDFDWKDYCPMVFRNLREM 430

  Fly   149 FGIQPDDFMMSMC-TSPLRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEFLQKLLPGYYMNLNQ 212
            |.:...|:|||:| ...|||:|:||.|||||||:.||.|:|||::..|.:.|.::||.||.::..
plant   431 FKLDAADYMMSICGDDGLREISSPGKSGSIFYLSHDDRFVIKTLKRSELKVLLRMLPRYYEHVGD 495

  Fly   213 NPRTLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKGSTFKRKANKAERAKKSPTY 277
            ...||:.||||::.::....|.:|.|||.|:..:.:|:|.:|||||||..|...|.:..:|: |.
plant   496 YENTLITKFFGVHRIKLKWGKKVRFVVMGNMFCTELKIHRRYDLKGSTQGRYTEKNKIGEKT-TL 559

  Fly   278 KDLDF-MEQHPNGIFLEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVHNLDVALKEKQSEQRK 341
            ||||. .|.|.:.:..|     ||.|.|..||:.|||.:|:|||||||:|       .:..:...
plant   560 KDLDLAYEFHMDKLLRE-----ALFKQIILDCSFLESLQILDYSLLLGLH-------FRAPDPLT 612

  Fly   342 PLRAPLAEDSDVDADDPLDGDAATGISRNKSVNRQRLVAHSTAMESIQAESEPI----------- 395
            .:..|..|.||.::|..  |.....:.|..|:..:.|:..:....|:.....|.
plant   613 DILEPPNEMSDQESDSV--GSVDVNLPREPSIPPKGLLMVTHEPNSVNTAPGPHIRGSTLRAFSV 675

  Fly   396 -DDEED-VPPG----------GIPARS---------EKGE-------RLLLYIGIIDILQSYRLK 432
             :.|.| :.||          .:||::         |.|.       .:::|:|||||||.|.:|
plant   676 GEKEVDLILPGTARLRVQLGVNMPAQAHHKLGQDNEESGTVELFEVYDVVVYMGIIDILQEYNMK 740

  Fly   433 KKLEHTFKSIIHDGETVSVCRPSFYAQRFQNFMAK 467
            ||:|||.||:.:|..|:|...|:.|::||.:|:.|
plant   741 KKVEHTCKSMKYDPMTISAIEPTLYSKRFIDFLLK 775

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIP5K59B	NP_001369113.1	PIPKc_PIP5KI	78..473	CDD:340438	157/469 (33%)
AT1G60890	NP_001185275.1	PLN03185	19..778	CDD:215619	174/555 (31%)
		MORN	74..96	CDD:280628
		MORN	120..142	CDD:280628
		MORN	141..162	CDD:197832
		MORN	168..187	CDD:280628
		PIPKc	384..777	CDD:214623	144/407 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	176	1.000	Domainoid score	I1082
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	250	1.000	Inparanoid score	I1030
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000462
OrthoInspector	1	1.000	-	-		mtm1094
orthoMCL	1	0.900	-	-		OOG6_100438
Panther	1	1.100	-	-	O	PTHR23086
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X284
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.820