Protein Alignment PIP5K59B and PIP4K2B

DIOPT Version :9

• Sequence 1: NP_001369113.1
• Gene: PIP5K59B / 37633
• FlyBaseID: FBgn0034789
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: XP_011523628.1
• Gene: PIP4K2B / 8396
• HGNCID: 8998
• Length: 443
• Species: Homo sapiens
• Alignment Length: 463
• Identity: 124/463 - (26%)
• Similarity: 206/463 - (44%)
• Gaps: 80/463 - (17%)

  Fly    46 PNRASSKADKERKIGHRRVGEGGEITYKKIQTSQ-IMGSIQLGIQHTVGSLASKPKRDLLMMDFW 109
            |..||....|::....::|        |..:.|: |:..:..|:.||:..|::.|...:||.|.:
Human    15 PLSASKTKTKKKHFVCQKV--------KLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDF 71

  Fly   110 ------EIESITFPPEGSSLTPAHHYSEFRYKIYAPIAFRYFRDLFGIQPDDFMMSMCTSPLREL 168
                  ::::..|..|...       |.|::|.|.|:.||..|:.|||...|:..|:..|.....
Human    72 KAYSKIKVDNHLFNKENLP-------SRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINS 129

  Fly   169 SNPGASGSIFYLTTDDEFIIKTVQHKEGEFLQKLLPGYYMNLNQ--------------------- 212
            .:.|..|:.|..|.|..|:||||..::...:..:|..|:.....
Human   130 DSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQMAGSLACLCILSLPCGIPISGWQKR 194

  Fly   213 -------NPRTLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKGSTFKRKANKAER 270
                   :..||||:|.|:|.| |.:.....:||..|:....:.:|.||||||||..|:|:..|:
Human   195 CKFIVECHGNTLLPQFLGMYRL-TVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEK 258

  Fly   271 AKKSPTYKDLDFMEQHPNGIFLEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVHNLDVALKEK 335
            ||..||:||.||:.:... :.:..|:....::.::||...|...||||||||:|:|::|.|.:|:
Human   259 AKDLPTFKDNDFLNEGQK-LHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEE 322

  Fly   336 QSEQRKPLRAPLAEDSDVDADDPLDGDAATGISRNKSVNRQRLVAHSTAME------SIQAESEP 394
            ...:.:      |||.:.:.|         |:..|      .|.::.|..:      |......|
Human   323 MEVEER------AEDEECEND---------GVGGN------LLCSYGTPPDSPGNLLSFPRFFGP 366

  Fly   395 IDDEEDVPPGGIPARSEKGERLLLYIGIIDILQSYRLKKKLEHTFKSIIHD-GETVSVCRPSFYA 458
            .:.:..|....:.:.....::.:.::.|||||..|..|||..|..|::.|. |..:|...|..|:
Human   367 GEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYS 431

  Fly   459 QRFQNFMA 466
            :||..||:
Human   432 KRFNEFMS 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP5K59B	NP_001369113.1	PIPKc_PIP5KI	78..473	CDD:340438	118/431 (27%)
PIP4K2B	XP_011523628.1	PIPKc	39..443	CDD:238081	118/431 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1562683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2198
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850