DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PIP5K59B and PIP5K4

DIOPT Version :9

Sequence 1:	NP_001369113.1	Gene:	PIP5K59B / 37633	FlyBaseID:	FBgn0034789	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_001319773.1	Gene:	PIP5K4 / 824863	AraportID:	AT3G56960	Length:	779	Species:	Arabidopsis thaliana

Alignment Length:	511	Identity:	173/511 - (33%)
Similarity:	247/511 - (48%)	Gaps:	115/511 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SGDGDTINTIDMDSSS-----ASQAKL-AE-------PSNASTDHVGNSSPDLGNRPNRASSKAD 54
            ||:|    ..|:||::     |...:| ||       ||.|..     ..|..|.:.....||
plant   332 SGEG----AADIDSTTRRDLDAEMMRLEAEGFIQSLRPSPAPM-----RLPRAGRKQGETISK-- 385

  Fly    55 KERKIGHRRVGEGGEITYKKIQTSQIMGSIQLGIQHTVGSLASKPKRDLLMMDFWEIESI--TFP 117
                 |||..              ::|.::||||:|.||..|.....||....|...|.:  .||
plant   386 -----GHRNY--------------ELMLNLQLGIRHAVGKQAPVVSLDLKHSAFDPKEKVWTRFP 431

  Fly   118 PEGSSLTPAHHYSEFRYKIYAPIAFRYFRDLFGIQPDDFMMSMC-TSPLRELSNPGASGSIFYLT 181
            |||:..||.|..|||::|.|.|:.||..|.||.:.|.|:|:|:| ...|||||:||.|||.||||
plant   432 PEGTKYTPPHQSSEFKWKDYCPLVFRSLRKLFKVDPADYMLSICGNDALRELSSPGKSGSFFYLT 496

  Fly   182 TDDEFIIKTVQHKEGEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCLQTSN--AKNIRLVVMNNLL 244
            .||.::|||::..|.:.|.::|..||.::.....||:.:|:||:|::.:.  .|.:|.|:|.||.
plant   497 NDDRYMIKTMKKSETKVLLRMLAAYYNHVRAFENTLVIRFYGLHCVKLTGPIQKKVRFVIMGNLF 561

  Fly   245 PSSVKMHLKYDLKGSTFKRKANKAERAKKSPT-YKDLDFMEQHPNGIF-LEAETYAALIKTIQRD 307
            .|...:|.::|||||:..|..:|.|....|.| .||||.     |.|| |:...|...|:.:.:|
plant   562 CSEYSIHRRFDLKGSSLGRTTDKPESEINSNTILKDLDL-----NFIFRLQKAWYQEFIRQVDKD 621

  Fly   308 CTVLESFKIMDYSLLLGVH--NLDVALKEKQSEQRKPL------RAPLAEDSDVDADDPLDGDAA 364
            |..||..:|||||||:|:|  ...||.:...|..|.|:      .||....:|||
plant   622 CEFLEQERIMDYSLLVGIHFREASVAGELIPSGARTPIGEFEDESAPRLSRADVD---------- 676

  Fly   365 TGISRNKSVNRQRLVAHSTAMESIQAESEPIDDEEDVPPGGIPARSEK----------------G 413
                        :|::..|...||:.            .|.:|||:|:                |
plant   677 ------------QLLSDPTRWASIRL------------GGNMPARAERTMRRSDCEFQLVGEPTG 717

  Fly   414 E--RLLLYIGIIDILQSYRLKKKLEHTFKSIIHDGETVSVCRPSFYAQRFQNFMAK 467
            |  .:::..|||||||.|.:.|||||.:|||.:|..::|...|..|::||::|:.|
plant   718 EYYEVVMIFGIIDILQDYDISKKLEHAYKSIQYDPTSISAVDPRLYSRRFRDFIFK 773

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIP5K59B	NP_001369113.1	PIPKc_PIP5KI	78..473	CDD:340438	153/423 (36%)
PIP5K4	NP_001319773.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	176	1.000	Domainoid score	I1082
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	250	1.000	Inparanoid score	I1030
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000462
OrthoInspector	1	1.000	-	-		mtm1094
orthoMCL	1	0.900	-	-		OOG6_100438
Panther	1	1.100	-	-	O	PTHR23086
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X284
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.820