DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PIP5K59B and PIP5K6

DIOPT Version :9

Sequence 1:	NP_001369113.1	Gene:	PIP5K59B / 37633	FlyBaseID:	FBgn0034789	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_187453.1	Gene:	PIP5K6 / 819987	AraportID:	AT3G07960	Length:	715	Species:	Arabidopsis thaliana

Alignment Length:	495	Identity:	167/495 - (33%)
Similarity:	249/495 - (50%)	Gaps:	82/495 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SSSASQAKLAE-PSNASTD-HVGNSSPDL---GNRPNRASSKADKER-KIGHRRV---GEGGEIT 71
            |||.::.|.:| |...|.| .|.|...:|   |:...:....|:..| .:|..|:   .:.|:..
plant   258 SSSGNRTKNSERPRRRSVDGRVSNGEMELRSNGSGYLQVDDNAESTRSSLGPLRIQPAKKQGQTI 322

  Fly    72 YKKIQTSQIMGSIQLGIQHTVGSLASKPKRDLLMMDFWEIESI--TFPPEGSSLTPAHHYSEFRY 134
            .|..:..::|.::||||:|:||..|.....||....|...|.:  .||.|||..||.|...||::
plant   323 SKGHKNYELMLNLQLGIRHSVGRPAPATSLDLKASAFDPKEKLWTKFPSEGSKYTPPHQSCEFKW 387

  Fly   135 KIYAPIAFRYFRDLFGIQPDDFMMSMC-TSPLRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEF 198
            |.|.|:.||..|.||.:...|:|:|:| ...|||||:||.|||.||||.||.::|||::..|.:.
plant   388 KDYCPVVFRTLRKLFSVDAADYMLSICGNDALRELSSPGKSGSFFYLTNDDRYMIKTMKKAETKV 452

  Fly   199 LQKLLPGYYMNLNQNPRTLLPKFFGLYCLQTSNA--KNIRLVVMNNLLPSSVKMHLKYDLKGSTF 261
            |.::||.||.::.....||:.|||||:|::.:..  |.:|.|:|.||..:...:|.::|||||:.
plant   453 LIRMLPAYYNHVRACENTLVTKFFGLHCVKLTGTAQKKVRFVIMGNLFCTGHSIHRRFDLKGSSH 517

  Fly   262 KRKANKAE-RAKKSPTYKDLDFMEQHPNGIF-LEAETYAALIKTIQRDCTVLESFKIMDYSLLLG 324
            .|...|.| ....:.|.||||.     |..| |:...:....:.:.|||..||..:|||||||:|
plant   518 GRLTTKPESEIDPNTTLKDLDL-----NFAFRLQKNWFQEFCRQVDRDCEFLEQERIMDYSLLVG 577

  Fly   325 VHNLDVALKEK---QSEQRKPLRAPLAEDSDVDADDPLDGDAATGISRNKSVNRQRLVAHSTAME 386
            :|..:.|:|:.   .|..|.|                 .|::.|.:||   ....|.:..::.:.
plant   578 LHFREAAIKDSATPTSGARTP-----------------TGNSETRLSR---AEMDRFLLDASKLA 622

  Fly   387 SIQAESEPIDDEEDVPPGGI--PARSEKGER------------------LLLYIGIIDILQSYRL 431
            ||:.              ||  |||.|:..|                  :::|.|||||||.|.:
plant   623 SIKL--------------GINMPARVERTARRSDCENQLVGDPTGEFYDVIVYFGIIDILQDYDI 673

  Fly   432 KKKLEHTFKSIIHDGETVSVCRPSFYAQRFQNFMAKTVFR 471
            .|||||.:||:.:|..::|...|..|::||::|    :||
plant   674 SKKLEHAYKSMQYDPTSISAVDPKQYSRRFRDF----IFR 709

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIP5K59B	NP_001369113.1	PIPKc_PIP5KI	78..473	CDD:340438	149/424 (35%)
PIP5K6	NP_187453.1	PLN03185	23..711	CDD:215619	167/495 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	176	1.000	Domainoid score	I1082
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	250	1.000	Inparanoid score	I1030
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000462
OrthoInspector	1	1.000	-	-		mtm1094
orthoMCL	1	0.900	-	-		OOG6_100438
Panther	1	1.100	-	-	O	PTHR23086
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X284
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.820