DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PIP5K59B and PIP5K5

DIOPT Version :9

Sequence 1:	NP_001369113.1	Gene:	PIP5K59B / 37633	FlyBaseID:	FBgn0034789	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_181654.1	Gene:	PIP5K5 / 818720	AraportID:	AT2G41210	Length:	772	Species:	Arabidopsis thaliana

Alignment Length:	527	Identity:	167/527 - (31%)
Similarity:	250/527 - (47%)	Gaps:	104/527 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GDTINTIDMDSSSASQAKLAEPSNASTDHVGNSSPDLGNRPNRAS---------SKADKERKIGH 61
            |:.:.|:      .||.||:         |.|||..: .:|.|.|         .:|.::..:..
plant   279 GERVPTL------PSQKKLS---------VWNSSKRI-EKPRRTSVDGRVSVGVDRAFEKMNMWG 327

  Fly    62 RRVGEGGEITYKKIQTS---------------------------------------QIMGSIQLG 87
            ..:||||....|::...                                       ::|.::|||
plant   328 NEIGEGGADMRKELDAELMRLDAEGLQSLKSSPVPMKLPKAGRKQGETISKGHRNYELMLNLQLG 392

  Fly    88 IQHTVGSLASKPKRDLLMMDFWEIESI--TFPPEGSSLTPAHHYSEFRYKIYAPIAFRYFRDLFG 150
            |:|:||..|.....||....|...:.|  .||.||:..||.|..:||::|.|.|:.||..|.||.
plant   393 IRHSVGRQAPAASLDLKPSAFDPKDKIWRRFPREGTKYTPPHQSTEFKWKDYCPLVFRSLRKLFK 457

  Fly   151 IQPDDFMMSMC-TSPLRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEFLQKLLPGYYMNLNQNP 214
            :.|.|:|:|:| ...|||||:||.|||.||||.||.::|||::..|.:.|..:|..||.::....
plant   458 VDPADYMLSICGNDALRELSSPGKSGSFFYLTNDDRYMIKTMKKSETKVLLGMLAAYYNHVRAFE 522

  Fly   215 RTLLPKFFGLYCLQTS--NAKNIRLVVMNNLLPSSVKMHLKYDLKGSTFKRKANKAERAKKSPT- 276
            .:|:.:||||:|::.:  ..|.:|.|:|.||..|...:|.::|||||:..|..:|.|....|.|
plant   523 NSLVIRFFGLHCVKLNGPTQKKVRFVIMGNLFCSKYSVHRRFDLKGSSLGRTTDKPESEIDSNTI 587

  Fly   277 YKDLDFMEQHPNGIF-LEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVH--NLDVALKEKQSE 338
            .||||.     |.|| |:...|...|:.|.:||..||..:|||||||:|:|  ...||.:...|.
plant   588 LKDLDL-----NFIFRLQKAWYQEFIRQIDKDCEFLEQERIMDYSLLVGIHFREASVAGELIPSG 647

  Fly   339 QRKPL------RAPLAEDSDVD--ADDPLDGDAATGISRNKSVNRQRLVAHSTAMESIQAESEPI 395
            .|.|:      ..|....::||  ..|| ...|:..:..|.....:|.:..:.:  .:|...||.
plant   648 ARTPIGESEEESGPRLSRAEVDELLSDP-SRWASIRLGTNMPARAERTMRKNDS--ELQLVGEPT 709

  Fly   396 DDEEDVPPGGIPARSEKGERLLLYIGIIDILQSYRLKKKLEHTFKSIIHDGETVSVCRPSFYAQR 460
            .:..:|               ::..|||||||.|.:.|||||.:|||.:|..::|...|..|::|
plant   710 GEFYEV---------------VMIFGIIDILQDYDISKKLEHAYKSIQYDPSSISAVDPRQYSRR 759

  Fly   461 FQNFMAK 467
            |::|:.|
plant   760 FRDFIFK 766

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIP5K59B	NP_001369113.1	PIPKc_PIP5KI	78..473	CDD:340438	148/446 (33%)
PIP5K5	NP_181654.1	PLN03185	66..768	CDD:215619	167/527 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	176	1.000	Domainoid score	I1082
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	250	1.000	Inparanoid score	I1030
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000462
OrthoInspector	1	1.000	-	-		mtm1094
orthoMCL	1	0.900	-	-		OOG6_100438
Panther	1	1.100	-	-	O	PTHR23086
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X284
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.820