DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PIP5K59B and PIP5K3

DIOPT Version :9

Sequence 1:	NP_001369113.1	Gene:	PIP5K59B / 37633	FlyBaseID:	FBgn0034789	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_001324179.1	Gene:	PIP5K3 / 817182	AraportID:	AT2G26420	Length:	719	Species:	Arabidopsis thaliana

Alignment Length:	475	Identity:	158/475 - (33%)
Similarity:	243/475 - (51%)	Gaps:	64/475 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 AEPSNASTDHVGNSSPDLGNRP-----NRASSKADKERKIGHRRVGEGGEITYKKIQTSQIMGSI 84
            |.|..:.:|..|....:....|     ..|.|.....|.:....|.:.|.......:...:|.::
plant   271 ASPYTSESDTSGCGEQEWARSPLLLESGGAMSVQQSPRWLDEGDVKKPGHTVTAGHKNYDLMLNL 335

  Fly    85 QLGIQHTVGSLASKPKRDLLMMDF------WEIESITFPPEGSSLTPAHHYSEFRYKIYAPIAFR 143
            ||||:::||..||. .|:|...||      |    ..||||||..||.|..:||::|.|.||.||
plant   336 QLGIRYSVGKHASL-LRELRHSDFDPKDKQW----TRFPPEGSKSTPPHLSAEFKWKDYCPIVFR 395

  Fly   144 YFRDLFGIQPDDFMMSMC-TSPLRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEFLQKLLPGYY 207
            :.||||.|...|:|:::| ...|||.::||.|||.||||.|:.::|||::..|.:.|.|:||.||
plant   396 HLRDLFAIDQADYMLAICGNESLREFASPGKSGSAFYLTQDERYMIKTMKKSEIKVLLKMLPNYY 460

  Fly   208 MNLNQNPRTLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKGSTFKRKANKAE-RA 271
            .::::...:|:.||||::|::....:..|.:||.||..|..::|.::|||||:..|..:|.| ..
plant   461 EHVSKYKNSLVTKFFGVHCVKPVGGQKTRFIVMGNLFCSEYRIHKRFDLKGSSHGRTIDKDEGEI 525

  Fly   272 KKSPTYKDLDFMEQHPNGIF-LEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVHNLDVALKE- 334
            .::.|.||||.     ..:| ||...:.|.|..|..||..||:.:|||||||:|:|..:..:::
plant   526 DETTTLKDLDL-----KYVFRLETSWFQAFINQIDLDCEFLEAERIMDYSLLIGLHFRESGMRDD 585

  Fly   335 ------KQSEQRKPLRA----PLAEDSDVDADDPLDGDAATGISRNKSVNRQRLVAHSTAMESIQ 389
                  ::.::.|.:|.    |..:......:.||                .||      .||..
plant   586 ISLGIGRRDQEDKLMRGYNSLPNMDSVTQTCNGPL----------------MRL------GESTP 628

  Fly   390 AESEPID--DEEDVPPGGIPARSEKGER-----LLLYIGIIDILQSYRLKKKLEHTFKSIIHDGE 447
            |::|.:.  :||......|...:.||.|     ::||.|:|||||.|.:.|||||.:||:..|..
plant   629 AKAEQVSRFEEETWEEDAIDNSNPKGTRKEAVEVILYFGVIDILQDYDITKKLEHAYKSLHADPA 693

  Fly   448 TVSVCRPSFYAQRFQNFMAK 467
            ::|...|..|::||::|:.|
plant   694 SISAVDPKLYSRRFRDFINK 713

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIP5K59B	NP_001369113.1	PIPKc_PIP5KI	78..473	CDD:340438	148/417 (35%)
PIP5K3	NP_001324179.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	176	1.000	Domainoid score	I1082
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	250	1.000	Inparanoid score	I1030
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000462
OrthoInspector	1	1.000	-	-		mtm1094
orthoMCL	1	0.900	-	-		OOG6_100438
Panther	1	1.100	-	-	O	PTHR23086
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X284
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.820