Protein Alignment PIP5K59B and pip5k1ca

DIOPT Version :9

• Sequence 1: NP_001369113.1
• Gene: PIP5K59B / 37633
• FlyBaseID: FBgn0034789
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: XP_009294612.1
• Gene: pip5k1ca / 798876
• ZFINID: ZDB-GENE-050208-358
• Length: 701
• Species: Danio rerio
• Alignment Length: 725
• Identity: 326/725 - (44%)
• Similarity: 413/725 - (56%)
• Gaps: 132/725 - (18%)

  Fly     2 ASGDGDTINTIDMDSSSASQAKLAEPSNASTDHVGNSSPDLGNRPNRASSKADKERKIGHRRVGE 66
            ||.|..:.:.:|.||.|........||::.....|                    :|||||.|..
Zfish    26 ASEDAGSADDVDADSISKKAFITEMPSSSGLPSHG--------------------KKIGHRGVDA 70

  Fly    67 GGEITYKKIQTSQIMGSIQLGIQHTVGSLASKPKRDLLMMDFWEIESITFPPEGSSLTPAHHYSE 131
            .||.||||..:|.:.|:|||||.:|||:|:|||:||:||.||:.:|||.||.|||:||||||:.:
Zfish    71 SGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFPD 135

  Fly   132 FRYKIYAPIAFRYFRDLFGIQPDDFMMSMCTSPLRELSNPGASGSIFYLTTDDEFIIKTVQHKEG 196
            ||:|.|||:||||||:||||:|||::.|:|..||.||||||||||:||||.|||||||||.|||.
Zfish   136 FRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYLTKDDEFIIKTVMHKEA 200

  Fly   197 EFLQKLLPGYYMNLNQNPRTLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKGSTF 261
            ||||||||||||||||||||||||||||||:| |..||||:|||||:||..|:|||||||||||:
Zfish   201 EFLQKLLPGYYMNLNQNPRTLLPKFFGLYCVQ-SGGKNIRMVVMNNVLPRVVRMHLKYDLKGSTY 264

  Fly   262 KRKANKAERAKKSPTYKDLDFMEQHPNGIFLEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVH 326
            ||:|:|.||.|..||:||||||::.|:|:.|:.:||.||:||:||||.|||||||||||||||||
Zfish   265 KRRASKKEREKAKPTFKDLDFMQELPDGLMLDTDTYNALVKTLQRDCLVLESFKIMDYSLLLGVH 329

  Fly   327 NLDVALKEKQSEQRKPLRAPLAEDSDVDADDPLDGDAATGISRNKSVNRQRLVAHSTAMESIQAE 391
            |:|.|.||:|.|         ....:.|...||...|                .::|||||||..
Zfish   330 NIDQAAKEQQME---------GSQGNSDEKRPLAQKA----------------LYTTAMESIQGA 369

  Fly   392 S---EPIDDEEDVPPGGIPARSEKGERLLLYIGIIDILQSYRLKKKLEHTFKSIIHDGETVSVCR 453
            |   |.||.::.:  |||||.:.:|||||||||||||||||||.||||||:|:::|||:||||.|
Zfish   370 SACGEGIDTDDTM--GGIPAVNGRGERLLLYIGIIDILQSYRLIKKLEHTWKALVHDGDTVSVHR 432

  Fly   454 PSFYAQRFQNFMAKTVFRKIPSLDLPEIKGNHRKFRTLVTSYIALKHSPSKRKSLSKAI------ 512
            |||||.||..||:.|||||..|                      ||.|||||.....|:
Zfish   433 PSFYADRFLRFMSSTVFRKTSS----------------------LKSSPSKRGRGGLAVGKYCGP 475

  Fly   513 -------QRSIDSDNEV----ASRPVHASHSHSSGKIHQPAKPPTTEPTPAGAAGGAERGATALG 566
                   |.....|..:    .:|............: .|..||:.|.....:.      ||.|.
Zfish   476 GAAWSASQLPFMRDENIYDLRGARSFPTLEDDGRADV-LPCTPPSFEEATTASI------ATTLS 533

  Fly   567 PATTSGASERAPP-----PVKQRTPAASNLKT--------------------RVPPPVPPRGSPR 606
            ..|:....||:|.     |..:|...:|:.:|                    ..|..|.|:.||.
Zfish   534 STTSLSIPERSPSDTSEHPRYRRHTQSSHEETMQDEDQQTITVEVEVEGRYDSEPTLVAPQVSPE 598

  Fly   607 RKDAQDRTTPGTEPHTTNPNPAPAHTHTLQVPANEGIPRFG-DRRSPSNVQDWLELHDLFDGPDS 670
            ..:|.: |.|.....:...:|      .:.|.::.|....| ..|:..:.:|.:.:.|::...|.
Zfish   599 ISEAAE-TIPEASSSSVPASP------RIVVESDGGSQASGCTSRASVDEEDDVPITDIYFFCDG 656

  Fly   671 GPYGPYAPPA 680
            ..:  ..|||
Zfish   657 SVH--VCPPA 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP5K59B	NP_001369113.1	PIPKc_PIP5KI	78..473	CDD:340438	257/397 (65%)
pip5k1ca	XP_009294612.1	PIPKc	108..448	CDD:214623	237/367 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	372	1.000	Domainoid score	I849
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	532	1.000	Inparanoid score	I1176
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1562683at2759
OrthoFinder	1	1.000	-	-		FOG0000462
OrthoInspector	1	1.000	-	-		mtm6440
orthoMCL	1	0.900	-	-		OOG6_100438
Panther	1	1.100	-	-	O	PTHR23086
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X284
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.830