Protein Alignment PIP5K59B and pip5k1a

DIOPT Version :10

• Sequence 1: NP_001369113.1
• Gene: PIP5K59B / 37633
• FlyBaseID: FBgn0034789
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: XP_031746234.1
• Gene: pip5k1a / 448746
• XenbaseID: XB-GENE-5748350
• Length: 608
• Species: Xenopus tropicalis
• Alignment Length: 671
• Identity: 307/671 - (45%)
• Similarity: 395/671 - (58%)
• Gaps: 150/671 - (22%)

  Fly    28 SNASTDHVGNSSPD--------LGNRP-NRASSKADKERKIGHRRVGEGGEITYKKIQTSQIMGS 83
            ::|:.:..|.:||.        :...| :.|...|...:|||||.|...||.||||..:|.:.|:
 Frog     2 ASAAAEPAGGTSPGTTTLKKSMVAEVPGSSAQPGAQTMKKIGHRGVDSTGETTYKKTTSSALKGA 66

  Fly    84 IQLGIQHTVGSLASKPKRDLLMMDFWEIESITFPPEGSSLTPAHHYSEFRYKIYAPIAFRYFRDL 148
            |||||.||||||::||:||:||.||:.:|||.||.|||:|||||||::||:|.|||:||||||:|
 Frog    67 IQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPGEGSNLTPAHHYNDFRFKTYAPVAFRYFREL 131

  Fly   149 FGIQPDDFMMSMCTSPLRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEFLQKLLPGYYMNLNQN 213
            |.|:|||::.|:|..||.||||||||||:||::.|||||||||||||.|||||||||||||||||
 Frog   132 FSIRPDDYLYSLCNEPLIELSNPGASGSVFYVSGDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQN 196

  Fly   214 PRTLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKGSTFKRKANKAERAKKSPTYK 278
            ||||||||:||||:| :..||||:||||||||.||:|||||||||||:||:|:..||.|||||||
 Frog   197 PRTLLPKFYGLYCVQ-AGGKNIRIVVMNNLLPRSVRMHLKYDLKGSTYKRRASAKEREKKSPTYK 260

  Fly   279 DLDFMEQHPNGIFLEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVHNLDVALKE------KQS 337
            ||||::..|:|:||:.:.:.||.|||||||.||:||||||||||:||||:|.|.||      .||
 Frog   261 DLDFLQDLPDGLFLDPDMHNALCKTIQRDCLVLQSFKIMDYSLLVGVHNMDCAQKETAVDGHTQS 325

  Fly   338 EQRKPLRAPLAEDSDVDADDPLDGDAATGISRNKSVNRQRLVAHSTAMESIQAESE---PIDDEE 399
            :.|:|                         :..|::       :||||||||.|:.   .|:.::
 Frog   326 DTRRP-------------------------AAQKAL-------YSTAMESIQGEARRGGAIETDD 358

  Fly   400 DVPPGGIPARSEKGERLLLYIGIIDILQSYRLKKKLEHTFKSIIHDGETVSVCRPSFYAQRFQNF 464
            .:  ||||||:.||||||||||:||:|||||..|||||::|:::|||:||||.||.|||.|||.|
 Frog   359 QM--GGIPARNAKGERLLLYIGVIDVLQSYRFMKKLEHSWKALVHDGDTVSVHRPGFYADRFQKF 421

  Fly   465 MAKTVFRKIPSLDLPEIKGNHRKFRTLVTSYIALKHSPSKRKSLSKAIQR--------------- 514
            |...||:|||                       ||.||||:......:.|
 Frog   422 MCSIVFKKIP-----------------------LKTSPSKKSRTMPGVSRRATQAAVPTQLQLVE 463

  Fly   515 ------SIDSDNEVASR-----------PVHASHSHS-----------SGKIHQPA--------- 542
                  :.:.::|..|:           ||..:.|.|           ||.::.||
 Frog   464 EHKQYLATEVESEPGSQFGRPDLLPRTPPVDEAASDSLATTLSTSSLGSGGLNSPAHRSVGVEVH 528

  Fly   543 KPPTT-------------EPTPAGAAGGAERGATALGPATTSGASERAPPPVKQRTPAASNLKTR 594
            |..||             |......|||.|....||         :.:....:.|....::.:..
 Frog   529 KVETTEIELNAVRSEVLDESNQEDEAGGEEEEEEAL---------DISQIETEIRFVRNADWRAH 584

  Fly   595 VPPPVPPRGSPRRKDAQDRTT 615
            :.||:|....|....|.|.|:
 Frog   585 LAPPLPHLAPPLPHLALDPTS 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP5K59B	NP_001369113.1	PIPKc_PIP5KI	78..473	CDD:340438	250/403 (62%)
pip5k1a	XP_031746234.1	PIPKc_PIP5K1A_like	58..432	CDD:340443	253/431 (59%)