Protein Alignment PIP5K59B and Pip5k1c

DIOPT Version :9

• Sequence 1: NP_001369113.1
• Gene: PIP5K59B / 37633
• FlyBaseID: FBgn0034789
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: XP_008763323.1
• Gene: Pip5k1c / 314641
• RGDID: 1309938
• Length: 692
• Species: Rattus norvegicus
• Alignment Length: 679
• Identity: 311/679 - (45%)
• Similarity: 406/679 - (59%)
• Gaps: 132/679 - (19%)

  Fly    57 RKIGHRRVGEGGEITYKKIQTSQIMGSIQLGIQHTVGSLASKPKRDLLMMDFWEIESITFPPEGS 121
            :|:|||.|...||.||||..:|.:.|:|||||.:|||:|:|||:||:||.||:.:|||.||.|||
  Rat    56 KKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGS 120

  Fly   122 SLTPAHHYSEFRYKIYAPIAFRYFRDLFGIQPDDFMMSMCTSPLRELSNPGASGSIFYLTTDDEF 186
            :||||||:.:||:|.|||:||||||:||||:|||::.|:|..||.||||||||||:||:|:||||
  Rat   121 NLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYVTSDDEF 185

  Fly   187 IIKTVQHKEGEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMH 251
            |||||.|||.|||||||||||||||||||||||||:||||:| |..||||:|||||:||..||||
  Rat   186 IIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQ-SGGKNIRVVVMNNVLPRVVKMH 249

  Fly   252 LKYDLKGSTFKRKANKAERAKKSPTYKDLDFMEQHPNGIFLEAETYAALIKTIQRDCTVLESFKI 316
            ||:||||||:||:|:|.|:.|..|||||||||:..|.|:.|:::|:.||:||:||||.|||||||
  Rat   250 LKFDLKGSTYKRRASKKEKEKSLPTYKDLDFMQDMPEGLLLDSDTFGALVKTLQRDCLVLESFKI 314

  Fly   317 MDYSLLLGVHNLDVALKEKQSEQRKPLRAPLAEDSDVDADDPLDGDAATGISRNKSVNRQRLVAH 381
            |||||||||||:|...:|:|           ||.:...||:            .:.|.::.|  :
  Rat   315 MDYSLLLGVHNIDQQERERQ-----------AEGAQSKADE------------KRPVAQKAL--Y 354

  Fly   382 STAMESIQ---AESEPIDDEEDVPPGGIPARSEKGERLLLYIGIIDILQSYRLKKKLEHTFKSII 443
            ||||||||   |..|.|:.::.:  |||||.:.:||||||:|||||||||||..||||||:|:::
  Rat   355 STAMESIQGGAARGEAIETDDTM--GGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALV 417

  Fly   444 HDGETVSVCRPSFYAQRFQNFMAKTVFRKIPSLDLPEIKGNHRKFRTLVTSYIALKHSPSKR--- 505
            |||:||||.||||||:||..||:.|||||..|                      ||.||||:
  Rat   418 HDGDTVSVHRPSFYAERFFKFMSSTVFRKSSS----------------------LKSSPSKKGRG 460

  Fly   506 -----KSLSKAIQRS---IDSDNEVASRPVHASHSHSSGKIHQPAKP---PTTEPTPAGAAGGAE 559
                 |.|......|   |.|:.|.....:..:.|:.:  :....:|   |.|.|:       .|
  Rat   461 ALLAVKPLGPTAAFSASQIPSEREDVQYDLRGARSYPT--LEDEGRPDLLPCTPPS-------FE 516

  Fly   560 RGATALGPATTSGAS----ERAP------PPVKQRTPAA---------------SNLKTRVPP-- 597
            ...||....|.|..|    ||:|      |..::||.::               ..:..:|.|
  Rat   517 EATTASIATTLSSTSLSIPERSPSDTSEQPRYRRRTQSSGQDGRPQEELHAEDLQKITVQVEPVC 581

  Fly   598 --------------PVPPRGSPRRKDAQ-DRTTPGTEPHTTNPNPAPAHTHTLQVPANEGIPRFG 647
                          .|||.|:......: |..:..:||.:...:...|.:..:...|:.....|.
  Rat   582 GVGVVVPKEQGAGVEVPPSGASAAATVEVDAASQASEPASQASDEEDAPSTDIYFFAHGRYWLFS 646

  Fly   648 DRR------------SPSNVQDWL--ELH 662
            .||            :|::.:.|:  .||
  Rat   647 PRRRQLRAVTPSHTGAPTDERSWVYSPLH 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP5K59B	NP_001369113.1	PIPKc_PIP5KI	78..473	CDD:340438	251/397 (63%)
Pip5k1c	XP_008763323.1	PIPKc	103..443	CDD:214623	231/367 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	363	1.000	Domainoid score	I912
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	496	1.000	Inparanoid score	I1334
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1562683at2759
OrthoFinder	1	1.000	-	-		FOG0000462
OrthoInspector	1	1.000	-	-		mtm8996
orthoMCL	1	0.900	-	-		OOG6_100438
Panther	1	1.100	-	-	O	PTHR23086
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X284
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.830