Protein Alignment PIP5K59B and its3

DIOPT Version :9

• Sequence 1: NP_001369113.1
• Gene: PIP5K59B / 37633
• FlyBaseID: FBgn0034789
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: NP_594429.1
• Gene: its3 / 2542231
• PomBaseID: SPAC19G12.14
• Length: 742
• Species: Schizosaccharomyces pombe
• Alignment Length: 586
• Identity: 178/586 - (30%)
• Similarity: 280/586 - (47%)
• Gaps: 103/586 - (17%)

  Fly    16 SSSASQAKLAEPSNA-STDHVGNSS----------PDLGNRPNRAS-SKADKERKIGHR------ 62
            |.|...:..||||.: |.|...|.|          ||:|:    || ::|.|::::..|
pombe   190 SYSEKNSSNAEPSGSRSGDRGTNVSTSGSLLDGIPPDIGS----ASWAEAVKQKRVNMRRRREEL 250

  Fly    63 ---------RVGEGGE--ITYKKIQTSQIMGSIQLGIQHTVGSLASKPKRDLLMMDFWEIESITF 116
                     ||.||.|  :|...:.|         ||:..|....:|..|:|...||......||
pombe   251 DDECVLVGTRVSEGHENYVTAYNMLT---------GIRVGVSRCQAKMDRELTPADFTARHKFTF 306

  Fly   117 PPEGSSLTPAHHYSEFRYKIYAPIAFRYFRDLFGIQPDDFMMSMCTSP--LRELSNPGASGSIFY 179
            ...|:.|||:..| :|::|.|||..||:.|.||.:...|:::|: ||.  |.||.:||.|||.||
pombe   307 DITGNELTPSAKY-DFKFKDYAPWVFRHLRQLFHLDAADYLVSL-TSKYILSELDSPGKSGSFFY 369

  Fly   180 LTTDDEFIIKTVQHKEGEFLQKLLPGYYMNLNQNPRTLLPKFFGLYCLQTSNAKNIRLVVMNNLL 244
            .:.|..|||||:.|.|.:||:::|..||.::..||.||:.:|:||:.::....:.|..||||||.
pombe   370 FSRDYRFIIKTIHHSEHKFLREILYDYYEHVKNNPNTLISQFYGLHRVKLPFGRKIHFVVMNNLF 434

  Fly   245 PSSVKMHLKYDLKGSTFKRKANKAERAKKSP--TYKDLDFMEQHPNGIF--LEAETYAALIKTIQ 305
            |....:|..:||||||..|:.::.:.. :||  |.||.:::.::.:..|  |:.:.:...:|.
pombe   435 PPHRDIHQTFDLKGSTLGRELDENQPC-QSPMCTMKDTNWIRRNMHLQFGPLKRQIFLTQVKA-- 496

  Fly   306 RDCTVLESFKIMDYSLLLGVHNLDVALKEKQSEQRKPLRAPLAEDSDVDADDP-LDGDAATGISR 369
             |..:|.|..|||||||:|:|:|....::|            ..:|.:...|| :.......|:.
pombe   497 -DIDMLSSLGIMDYSLLVGIHDLSRGNRDK------------IRNSILSVYDPNVSQHRVPSING 548

  Fly   370 NKS---VNRQRLVAHSTAMESIQAESEPIDDEEDV---------PPGGIPARSEKGE--RLLLYI 420
            |:|   |:..|.|.:||...|:......:..::.|         ..||..|..|..|  ..:.||
pombe   549 NESHSNVHVIRQVVNSTGPVSLDQSCNLLPTDQFVERRNFMFYSDDGGFQATDENNEPGNFIFYI 613

  Fly   421 GIIDILQSYRLKKKLEHTFKSIIHDGETVSVCRPSFYAQRFQNFMAKTVFRKIPSLDLPEIKGNH 485
            ||||:|..|...|::||.:|.|.|....:|...|:.||.||..|:..::   .|:|
pombe   614 GIIDLLTKYSYVKRVEHLWKGINHSDSVISAVPPAEYASRFYKFVESSI---KPTL--------- 666

  Fly   486 RKFRTLVTSYIALKHSPSKRKSLSKAIQRSIDSDNEVASRPVHASHSHSSGKIHQPAKPPTTEPT 550
                 ||.....||  |...:.::|  |:|:::.| |.:...|.|.::::....:.||..:...:
pombe   667 -----LVLKPFPLK--PQDGQRVNK--QQSVNAGN-VRTNNKHGSLNNNTAPSSRNAKSTSAHKS 721

  Fly   551 P 551
            |
pombe   722 P 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP5K59B	NP_001369113.1	PIPKc_PIP5KI	78..473	CDD:340438	136/415 (33%)
its3	NP_594429.1	MSS4	1..667	CDD:227578	163/524 (31%)
		PIPKc	294..662	CDD:214623	130/385 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1030
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	200	1.000	Inparanoid score	I996
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000462
OrthoInspector	1	1.000	-	-		otm47073
orthoMCL	1	0.900	-	-		OOG6_100438
Panther	1	1.100	-	-	O	PTHR23086
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2198
SonicParanoid	1	1.000	-	-		X284
TreeFam	1	0.960	-	-
	11	10.850