Protein Alignment PIP5K59B and Pip4k2a

DIOPT Version :9

• Sequence 1: NP_001369113.1
• Gene: PIP5K59B / 37633
• FlyBaseID: FBgn0034789
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: NP_032871.3
• Gene: Pip4k2a / 18718
• MGIID: 1298206
• Length: 405
• Species: Mus musculus
• Alignment Length: 454
• Identity: 114/454 - (25%)
• Similarity: 209/454 - (46%)
• Gaps: 65/454 - (14%)

  Fly    24 LAEPSNASTDHVGNSSPDLGNRPNRASSKADKERKIGHRRVGEGGEITYKKIQTSQ-IMGSIQLG 87
            :|.|.|            ||:....:.:|..|:..:..:         .|..:.|. ::..:..|
Mouse     1 MATPGN------------LGSSVLASKTKTKKKHFVAQK---------VKLFRASDPLLSVLMWG 44

  Fly    88 IQHTVGSLASKPKRDLLMMDFW------EIESITFPPEGSSLTPAHHYSEFRYKIYAPIAFRYFR 146
            :.|::..|:......:||.|.:      ::::..|..|.   .|:|    |::|.|.|:.||..|
Mouse    45 VNHSINELSHVQIPVMLMPDDFKAYSKIKVDNHLFNKEN---MPSH----FKFKEYCPMVFRNLR 102

  Fly   147 DLFGIQPDDFMMSMCTSPLRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEFLQKLLPGYYMNLN 211
            :.|||...||..|:..|......:...||:.|:.:.|..::|||:..::...:..:|..|:..:.
Mouse   103 ERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYVIKTITSEDVAEMHNILKKYHQYIV 167

  Fly   212 Q-NPRTLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKGSTFKRKANKAERAKKSP 275
            : :..||||:|.|:|.|.....: |.::|..|:....:.::.||||||||..|:|:..|:||:.|
Mouse   168 ECHGVTLLPQFLGMYRLNVDGVE-IYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELP 231

  Fly   276 TYKDLDFMEQHPNGIFLEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVHNLDVALKEKQSEQR 340
            |.||.||:.:... |:::.......::.:::|...|...|:||||||:|:|:::.|.:|:..
Mouse   232 TLKDNDFINEGQK-IYIDDNNKKIFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVE--- 292

  Fly   341 KPLRAPLAEDSDVDADDPLDGDAATGI---SRNKSVNRQRLVAHSTAMESIQAESEPIDDEEDVP 402
                   .|::|.:.:...|.....|.   |...::|....:|             |.:.:.::.
Mouse   293 -------CEENDGEEEGESDSTHPIGTPPDSPGNTLNSSPPLA-------------PGEFDPNID 337

  Fly   403 PGGIPARSEKGERLLLYIGIIDILQSYRLKKKLEHTFKSIIHD-GETVSVCRPSFYAQRFQNFM 465
            ...|........:.:.::.|||||..|..|||..|..|::.|. |..:|...|..|::||.:|:
Mouse   338 VYAIKCHENAPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFI 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP5K59B	NP_001369113.1	PIPKc_PIP5KI	78..473	CDD:340438	106/400 (27%)
Pip4k2a	NP_032871.3	Required for interaction with PIP5K1A. /evidence=ECO:0000250|UniProtKB:Q8TBX8	59..65		2/5 (40%)
		PIPKc	62..405	CDD:214623	101/372 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	288..328		7/49 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2198
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840