Protein Alignment PIP5K59B and PIP5KL1

DIOPT Version :9

• Sequence 1: NP_001369113.1
• Gene: PIP5K59B / 37633
• FlyBaseID: FBgn0034789
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: NP_001128691.1
• Gene: PIP5KL1 / 138429
• HGNCID: 28711
• Length: 394
• Species: Homo sapiens
• Alignment Length: 448
• Identity: 101/448 - (22%)
• Similarity: 182/448 - (40%)
• Gaps: 75/448 - (16%)

  Fly    24 LAEPSNASTDHVGNSSPDLGNRPNRASSKA------DKERKIGHRRVGEGGEI-TYKKIQTSQIM 81
            :|.||....: |...||:.|.|...:|.:.      ||:.::|...:..|.|: ....:..:.:.
Human     1 MAAPSPGPRE-VLAPSPEAGCRAVTSSRRGLLWRLRDKQSRLGLFEISPGHELHGMTCMMQAGLW 64

  Fly    82 GSIQLGIQHTVGSLASKPKRDLLMMDFWEIESITFPPEGSSLTPAHHYSEFRYKIYAPIAFRYFR 146
            .:.|:.:.|..   ...|.||    ||.|:           ||..|  ..|.....|..||.:.|
Human    65 AATQVSMDHPP---TGPPSRD----DFSEV-----------LTQVH--EGFELGTLAGPAFAWLR 109

  Fly   147 DLFGIQPDDFMMSMCT-SPLRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEFLQKLLPGYYMNL 210
            ...|:..:|:..::.. .|..:..:...|.:.|:|:.|..|.:||...:|.:.|...||.|..:|
Human   110 RSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLSHDQRFFLKTQGRREVQALLAHLPRYVQHL 174

  Fly   211 NQNPRTLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKGSTFKRKANKAERAKKSP 275
            .::|.:||.:..|::.|:....|....:||.::...:.::..:||:||....|..:.|...  ||
Human   175 QRHPHSLLARLLGVHSLRVDRGKKTYFIVMQSVFYPAGRISERYDIKGCEVSRWVDPAPEG--SP 237

  Fly   276 ---TYKDLDFMEQHPNGIFLEAETYAALIKTIQRDCTVLESFKIMDYSLLLGVHNLDVALKEKQS 337
               ..|||:|..:..|    .....:..::.::.|.|.|....::|||||       :|.:....
Human   238 LVLVLKDLNFQGKTIN----LGPQRSWFLRQMELDTTFLRELNVLDYSLL-------IAFQRLHE 291

  Fly   338 EQRKPLRAPLAEDSDVDADDPLDGDAATGISRNKSVNRQRLVAHSTAMESIQAESEPIDDEEDVP 402
            ::|.|       .|.:..........|.....:::.||:.|.....|:..:.
Human   292 DERGP-------GSSLIFRTARSVQGAQSPEESRAQNRRLLPDAPNALHILD------------- 336

  Fly   403 PGGIPARSEKGERLLLYIGIIDILQSYRLKKKLEHTFKSIIHDGETVSVCRPSFYAQR 460
                      |.....::|::|:...|.|:|:|||.:|::.:.|.|.|...|:.||:|
Human   337 ----------GPEQRYFLGVVDLATVYGLRKRLEHLWKTLRYPGRTFSTVSPARYARR 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP5K59B	NP_001369113.1	PIPKc_PIP5KI	78..473	CDD:340438	87/387 (22%)
PIP5KL1	NP_001128691.1	PIP5K	128..392	CDD:279801	69/300 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1562683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23086
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920