DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PIP5K59B and pip5kl1

DIOPT Version :9

Sequence 1:	NP_001369113.1	Gene:	PIP5K59B / 37633	FlyBaseID:	FBgn0034789	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	XP_021327291.1	Gene:	pip5kl1 / 100149843	ZFINID:	ZDB-GENE-060526-248	Length:	470	Species:	Danio rerio

Alignment Length:	490	Identity:	117/490 - (23%)
Similarity:	194/490 - (39%)	Gaps:	107/490 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 SSPDLGNRPNRASSKADKERKIGHRRVGEGGEITYKKIQTSQIMGSIQLGIQHTVGSLA------ 96
            |.|.:..|     |:..|.|:.|..|            |..:::|..::..:|...||.
Zfish    11 SGPSVNRR-----SRTVKRRRWGGLR------------QQWKLLGLFEIDQEHEFHSLTCMMKEG 58

  Fly    97 ---------SKPKRDLLMMDFWEIESITFPPEGSSLTPAHHYSEFRYKIYAPIAFRYFRDLFGIQ 152
                     ..|..|.|..|.:.:|          :|..|  .:||.:.||...|...|...|:.
Zfish    59 LRAAVQNTIDNPLPDELCEDDYSLE----------VTQIH--KDFRMETYAGPVFASLRRSLGMT 111

  Fly   153 PDDFMMSMCTSP--LRELSNPGASGSIFYLTTDDEFIIKTVQHKEGEFLQKLLPGYYMNLNQNPR 215
            ..::..|:.:..  |:.:|| ..|.:.|:||.|..|.:||...:|..||...|..|..:|.:.|.
Zfish   112 EKEYQQSLSSEGCYLQFISN-SKSKADFFLTNDKRFFLKTQSKREVRFLLSNLRIYMEHLEKYPH 175

  Fly   216 TLLPKFFGLYCLQTSNAKNIRLVVMNNLLPSSVKMHLKYDLKGSTFKRKANKA-ERAKKSPTYKD 279
            :||.||.|::.::.:|.:....:||.::.....::..:||:||....|..:.| |.:......||
Zfish   176 SLLVKFLGVHRIKIANQRKKYFIVMQSVFYPDDRIMARYDIKGCEVSRWTDPAPEGSHIIVVLKD 240

  Fly   280 LDFMEQHPNGIFLEAETYAA-LIKTIQRDCTVLESFKIMDYSLLLG---VH------NLDVALKE 334
            |:|     .|.|:..:.... |::.::.|...|::..::||||||.   :|      :|..|...
Zfish   241 LNF-----EGQFIHLDQQRPWLLRQVEIDTAFLQTLNVLDYSLLLAHQPLHQDELSQSLSFATLI 300

  Fly   335 KQSEQRKPL--RAPLAEDS----------------DVDADD---PL------------------D 360
            .::::..|.  :.|||..|                .|.||:   ||                  |
Zfish   301 MRTKKSFPFFSKRPLAGRSVNPVSSPTHAASPTVPGVVADEDSSPLPSELNCTHNSHITECSGND 365

  Fly   361 GDAATGISRNKSVNRQRLVAHSTAMESIQAESEPIDDEEDVPPGGIPARSEKGERLLLYIGIIDI 425
            |...|.:.........|..|.|..:::.|:::..:     :|....|.....|.....:||||||
Zfish   366 GMDNTSLEGENIEGPSRAGAESADLQAFQSQNRRL-----LPNFKNPLHVIDGPEQRYFIGIIDI 425

  Fly   426 LQSYRLKKKLEHTFKSIIHDGETVSVCRPSFYAQR 460
            ...|..:|:|||.:|.:.|..:|.|...|..|..|
Zfish   426 FTVYGFRKRLEHLWKRLRHPSQTFSTVSPPAYCHR 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIP5K59B	NP_001369113.1	PIPKc_PIP5KI	78..473	CDD:340438	108/450 (24%)
pip5kl1	XP_021327291.1	PIP5K	124..468	CDD:307586	89/348 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1562683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23086
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920